Patent Classification

Biology/Culture/Cell Line, Cell/Bacteria/Tissue/Virus/Receptor

1. Outer membrane vesicles and uses thereof
    
2. Preparing a population of human late stage motor neuron progenitor cells
    
3. Method for evaluating cell populations
    
4. Human immortalised neural precursor cell line
    
5. Targeted modification of chromatin structure
    
6. Method of cell storage in a delivery system comprising a fibrous matrix
    
7. Method of separating tumor cells with and without lymphotropic metastatic potential in a human carcinoma
    
8. Cell cycle arrest and apoptosis
    
9. Method for rapid generation of mature dendritic cells
    
10. Method for obtaining new life forms
     
11. Intracellular production of a nuclease
     
12. Compositions and methods for the control of mammary cell number
     
13. Methods and systems for imaging cells
     
14. Cells containing a nanopatch sensor in their membrane
     
15. Method for chemical dissociation of cells from physical surfaces
     
16. Proteins having effects of controlling cell migration and cell death
     
17. Exocrine gland tight junction-constituting protein jeap family
     
18. Methods of controlling cell differentiation and growth using a fusion protein and a drug
     
19. Antibody composition-producing cell
     
20. Methods of isolating specific compounds from supramammary lymph node tissue
     
21. Generating vascular smooth muscle cells in vitro from ES cells
     
22. System and method for inhibiting cellular proliferation with tachykinins
     
23. In vitro tumor angiogenesis model
     
24. Cell division marker
     
25. Cultures of GFAP.sup.+ nestin.sup.+ cells that differentiate to neurons
     
26. Method for generating engineered cells by homologously recombining segments having increased degeneracy
     
27. Method for cultivating cells, particularly human or animal cells
     
28. Method for determining a product secretion profile of cells
     
29. Method for sorting tumor cells
     
30. Combined regulation of neural cell production
     
31. Alginate gel scaffold having a plurality of continuous parallel microtubular copper capillaries
     
32. Variants of human taste receptor genes
     
33. Composition and method of using carcinoma tumor cells
     
34. Antibodies for identifying and/or isolating at least one cell population which is selected from the group comprising haematopoietic stem cells, neuronal stem cells, neuronal precursor cells, mesenchymal stem cells and mesenchymal precursor cells
     
35. Purified mammalian Flt3 ligands; agonists; antagonists
     
36. Methods and compositions for increasing longevity and protein yield from a cell culture
     
37. Adult stem cell lines
     
38. Emissive species for clinical imaging
     
39. Mammalian immortalized liver cell
     
40. Cell lysis by heating-cooling process through endothermic reaction
     
41. Postpartum cells isolated from umbilical cord tissue, and methods of making and using the same
     
42. Method for measuring the vitality of cells
     
43. Method for identifying compounds modulating taste transduction
     
44. Genetic construct intracellular monitoring system
     
45. Method for producing dendritic cells
     
46. Mannitol induced promoter systems in bacterial host cells
     
47. Method for controlling biological function with mechanical vibration and device therefor
     
48. Adenosine receptor
     
49. Multi plasmid system for the production of influenza virus
     
50. Beads for capturing target cells from bodily fluid
     
51. Method of purification of cells
     
52. Chronic lymphocytic leukemia cell line
     
53. Use of nerve growth factor for the storage, culture or treatment of cornea
     
54. Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
     
55. Cell lines
     
56. Replication of hepatitis C virus in non-hepatic epithelial and mouse hepatic cells
     
57. Culture system for rapid expansion of human embryonic stem cells
     
58. Cell fusion method
     
59. Methods for immortalizing cells
     
60. Estrogen receptor genes and utilization thereof
     
61. Human myeloma cell line
     
62. Packaging cell lines for the continuous production of alphavirus vectors
     
63. In vivo synthesis of connective tissues
     
64. Akt compositions for enhancing survival of cells
     
65. Method for generating diversity
     
66. Production of urokinase in a three-dimensional cell culture
     
67. Generating vascular smooth muscle cells in vitro from ES cells
     
68. System and method for forming a cardiac muscle construct
     
69. Methods of adenovirus purification
     
70. Assay for distinguishing live and dead cells
     
71. Growth factor homolog ZVEGF4
     
72. Genes encoding genetic stability, gene expression and folding proteins
     
73. Modulators of the function of FAS/APO1 receptors
     
74. Method for generating hypermutable organisms
     
75. Methods and means for influencing intracellular communication and intracellular organelle transport
     
76. Immortalized vascular adventital cell line
     
77. Process for the in vitro culture of different stages of tissular parasites
     
78. Method of effecting a change in a cell, and a vector
     
79. Insulin-secreting immortalized liver cell line modified by glucose sensitivity
     
80. Processes for culturing E1-immortalized cells to increase product yields
     
81. Molecular regulatory circuits to achieve sustained activation of genes of interest by a single stress
     
82. Plus end-directed microtubule motor required for chromosome congression
     
83. Method for identifying Listeria monocytogenes and culture medium
     
84. Method for obtaining a purified viral preparation
     
85. Cell lines for the propagation of mutated herpes viruses
     
86. Method for antimicrobial susceptibility testing of microorganisms
     
87. Characterizing biological stimuli by response curves
     
88. Prostate cancer cell lines
     
89. Method for determining cell cycle position
     
90. Peptide leukotriene receptor
     
91. Clonal cultures of primate embryonic stem cells
     
92. Methods of producing neurons
     
93. Method of extracting virus from cell culture
     
94. Cell culture system for synthesis of infectious hepatitis C virus
     
95. Methods to culture circovirus
     
96. Lyophilization of human platelets
     
97. Cultured cells from pancreatic islets
     
98. Method of treating biological cells and/or their cell components with electrical fields
     
99. Methods for enhancing the production of viral vaccines in cell culture
     
100. Method for selectively separating live cells expressing a specific gene
      
101. Targeted system for removing tumor cells from cell populations
      
102. Method for the production and purification of adenoviral vectors
      
103. Detection of transmembrane potentials by optical methods
      
104. Composition for the preservation of viruses
      
105. Cell concentration and lysate clearance using paramagnetic particles
      
106. Escherichia coli strain secreting human granulocyte colony stimulating factor (G-CSF)
      
107. Detection of protein conformations in single cells
      
108. Production of cultured human mast cells and basophils for high throughput small molecule drug discovery
      
109. Cell culture performance with betaine
      
110. Bioartificial device for the storage, cultivation and/or multiplication of cells
      
111. DNA encoding novel estrogen receptor
      
112. Culture of goblet cells
      
113. Spheroid preparation
      
114. Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering
      
115. Cells for drug discovery
      
116. Process for scaled-up production of recombinant proteins using transgenic plant suspension cultures
      
117. Cancer cell-inhibiting culture medium produced by culturing restricted entrapped cancer cells
      
118. Netrin receptors
      
119. Cell culture system for determining the cholesterol efflux potential for serum
      
120. Use of Acacia Gum to isolate and preserve biological material
      
121. Method and apparatus for destroying dividing cells
      
122. Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
      
123. Implanting neural progenitor cells derived for human embryonic stem cells
      
124. Method for modulating nerve cell function
      
125. Cold storage solution for organ and biological tissue preservation
      
126. Nucleic acid sequences and proteins involved in cellular senescence
      
127. Method for in vitro propagation of the agent responsible for transmissible spongiform encephalopathies
      
128. Cells for drug discovery
      
129. Immortal human prostate epithelial cell lines and clones and their applications in the research and therapy of prostate cancer
      
130. Composition and method for culturing potentially regenerative cells and functional tissue-organs in vitro
      
131. Use of human prostrate cell lines in prostate cancer treatment
      
132. Methods of modifying cell structure and remodeling tissue
      
133. Method for the selective survival or selective growth of a target cell by the use of a conjugate, its use in therapeutics and/or diagnostics and the preparation of said conjugate
      
134. Death domain proteins
      
135. Methods of controlling proliferation and differentiation of stem and progenitor cells
      
136. Methods for lyophilizing competent cells
      
137. Antigen activating method and antigen activator
      
138. Laminin chains: diagnostic uses
      
139. Self-replicating RNA molecule from hepatitis C virus
      
140. Method for large scale production of virus antigen
      
141. Genes displaying enhanced expression during cellular senescence and terminal cell differentiation and uses thereof
      
142. Cell regulatory genes, encoded products, and uses related thereto
      
143. Epidermal melanocyte culture formulations
      
144. Method of determining biological/molecular age
      
145. Culture system for mouse tracheal epithelial cells
      
146. Lineage specific cells and progenitor cells
      
147. Human ovarian mesothelial cells and methods of isolation and uses thereof
      
148. Telomerase
      
149. Medium containing flt3 ligand for culturing hematophoietic cells
      
150. Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor
      
151. Megakaryocytic protein tyrosine kinase I
      
152. Simultaneous stimulation and concentration of cells
      
153. Process for obtaining mammalian insulin secreting cells in vitro and their uses
      
154. Preparation of porous silicone rubber for growing cells or living tissue
      
155. Multiparameter FACS assays to detect alterations in exocytosis
      
156. Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays
      
157. Selective precipitation of viruses
      
158. Three-dimensional hydrogel/cell system
      
159. Method for labeling individual cells
      
160. Characterization of novel gene cbl-SL
      
161. Fast method of transforming competent cells
      
162. Methods and compositions for destabilizing microtubules
      
163. Methods and interferon deficient substrates for the propagation of viruses
      
164. Gene cluster screening of clones having DNA from mixed populations of organisms
      
165. Hybrid cells
      
166. Genetically modified fibroblast cells
      
167. Methods for using annexin for detecting cell death in vivo and treating associated conditions
      
168. Herpes virus complementing cell line
      
169. Method of stimulating epithelial cells using keratinocyte growth factor (KGF) and method of inhibiting KGF activity
      
170. Production of replicative hepatitis C virus
      
171. Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell
      
172. Antibodies to receptor protein tyrosine kinases
      
173. Methods for storing neural cells
      
174. Human cyclin-dependent kinase-like proteins and methods of using the same
      
175. Methods of making pancreatic islet cells
      
176. Discovery, localization, harvest, and propagation of an FGF2 and BDNF-responsive population of neural and neuronal progenitor cells in the adult human forebrain
      
177. Mouse mammary tumor lines expressing estrogen and progesterone receptors
      
178. Method of extracting virus from cell culture
      
179. Preparation for use in cell culture in which an interfering compound is absent or depleted
      
180. Simultaneous stimulation and concentration of cells
      
181. Regulated autocrine growth of mammalian cells
      
182. Method for identifying polymorphic markers in a population
      
183. Cell culture harvesting
      
184. Cell expansion system for use in neural transplantation
      
185. Bacteriophage, a process for the isolation thereof, and a universal growth medium useful in the process thereof
      
186. Immortalized human microglia cell line
      
187. Cancer cell-inhibiting culture medium produced by culturing restricted entrapped cancer cells
      
188. Protein free formulations
      
189. Prostate cancer cell lines
      
190. Transferring materials into cells using porous silicon
      
191. Mammalian myeloid progenitor cell subsets
      
192. Human cell line showing stable expression of cytochromes P450
      
193. Method for separating cells using immunorosettes
      
194. Long-term three dimensional tissue culture system
      
195. Receptor-mediated uptake of an extracellular BCL-xL fusion protein inhibits apoptosis
      
196. Stable human oral cancer cell carcinoma cell line
      
197. Keratinocyte cultures and uses thereof
      
198. Method of imaging cell death in vivo
      
199. Directed evolution of microorganisms
      
200. Method of producing infectious reovirus
      
201. In vivo induction for enhanced function of isolated hepatocytes
      
202. Gastric submucosal tissue as a novel diagnostic tool
      
203. Dendritic cells; methods
      
204. Composition and method for production of transformed cells
      
205. Human cancer cell line malignantly altered by expression of angiogenic factor
      
206. Metabolically engineered lactic acid bacteria and their use
      
207. Human glucose-dependent insulin-secreting cell line
      
208. Platform for the differentiation of cells
      
209. Methods and compositions for increasing protein yield from a cell culture
      
210. Methods for the screening of non-recombinant cell lines capable of expressing a single PDE4 isoenzyme and for the screening of PDE4 inhibitors
      
211. Monolayer sheet structure of primary hepatocytes obtained using a protein-phosphorylation inhibitor
      
212. Method for treatment of an aqueous flux by electropulsation of a field parallel to the flow, pulsation chamber and uses thereof
      
213. Serum-free cell growth medium
      
214. Antibodies to NIMA interacting proteins
      
215. Preparing porous biodegradable polymeric scaffolds for tissue engineering using effervescent salts
      
216. FADD-like anti-apoptotic molecules, methods of using the same, and compositions for and methods of making the same
      
217. Immortalized cell line derived from normal human skin tissues
      
218. Chlamydia-free cell lines and animals
      
219. Permanent amniocytic cell line, its production and use for the production of gene transfer vectors
      
220. Media for culturing human cells comprising human serum and method for culturing human cells using the same
      
221. Sialidase localized in plasma membrane DNA coding for the same
      
222. Protein-induced morphogenesis in liver tissue
      
223. Methods of using BCL-2 for the therapeutic treatment and prevention of diseases
      
224. Method and composition for preserving viruses
      
225. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII for binding cells
      
226. Zinc ionophores as therapeutic agents
      
227. Inhibitors of cell-cycle progression and uses related thereto
      
228. Cell-cycle regulatory proteins, and uses related thereto
      
229. In situ growth, freezing and testing of cultured cells
      
230. Method of promoting cellular function
      
231. Molecules associated with the human suppressor of fused gene
      
232. Purposeful movement of human migratory cells away from an agent source
      
233. Material for activating epidermal cell multiplication
      
234. Stimulation of cell proliferation by glycosylated cystatin C
      
235. Immortal cell line derived from grouper Epinephelus coioides and its application therein
      
236. Device and process for cell capture and recovery
      
237. Death domain containing receptor-4
      
238. Polysaccharide sponges for cell culture and transplantation
      
239. Antiproliferative Sgk reagents and methods
      
240. Nucleic acid construct for the cell cycle regulated expression of structural genes
     
     
241. Submucosa extracts
     
     
242. Methods of making conditioned cell culture medium compositions
     
     
243. Broad specificity DNA damage endonuclease
     
     
244. Hypoxia mediated neurogenesis
     
     
245. Modulation of multicellular aggregates by pressure from growth in a matrix
     
     
246. Osteocyte cell lines
     
     
247. Transcriptional inhibitor
     
     
248. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
     
     
249. Semaphorin-specific antibodies
     
     
250. Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
      
     
251. Cell growth accelerator and cell growth method using the same
      
     
252. Use of mCRP to slow cell growth and to promote maturation of cells
      
     
253. Methods for determining gluconeogenesis, anapleurosis and pyruvate recycling
      
     
254. Method for increasing life-span
      
     
255. Medium and matrix for long-term proliferation of cells
      
     
256. Anti-mitotic agent screening process
      
     
257. Human signal transduction serine/threonine kinase
      
     
258. Process and culture medium for the production of cells infected by a multiple sclerosis-associated virus
      
     
259. flt3-L mutants and method of use
      
     
260. Immortalized human corneal epithelial cell line
      
     
261. Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
      
     
262. Submucosa as a growth substrate for cells
      
     
263. Expression monitoring of downstream genes in the BRCA1 pathway
      
     
264. Method of using hedgehog polypeptides to regulate neuronal cell growth
      
     
265. Method of imaging cell death in vivo
      
     
266. Method of increasing cell renewal rate

Biomaterials

1. Biomaterial derived from vertebrate liver tissue
    
2. Hydrophilic polymer biomaterial having a specific magnetic resonance imaging signal and process for the preparation of said biomaterial
    
3. Composition derived from biological materials and method of use and preparation
    
4. Polymer blends as biodegradable matrices for preparing biocomposites
    
5. Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
    
6. Preservation of bioactive materials by spray drying
    
7. Hyaluronic acid gel, process for producing the same, and medical material containing the same
    
8. Coumarin endcapped absorbable polymers
    
9. Direct encapsulation of biomacromolecules in surfactant templated mesoporous and nanoporous materials
    
10. Mineralization and biological modification of biomaterial surfaces
     
11. Surfactants that mimic the glycocalyx
     
12. Fermentation method with continuous mass cultivation of ciliates (protozoa) for producing biogenous valuable substances
     
13. Biopolymer nanoparticles
     
14. Drug-loaded biological material chemically treated with genipin
     
15. Anticalcification treatments for fixed biomaterials
     
16. Biomaterial derived from vertebrate liver tissue

Biosensor

1. Detection of biotargets using bioreceptor functionalized nanoparticles
    
2. Neurotransmitter sensors and methods of using the same
    
3. Hydrogel functionalized with a polymerizable moiety and their uses as biosensors or bioreactors
    
4. Biomolecule immobilisation using atmospheric plasma technology
    
5. Measurement method using biosensor
    
6. Bio-sensor and bio-sensor reporting system
    
7. Silica mesoporous aerogels having three-dimensional nanoarchitecture with colloidal gold-protein superstructures nanoglued therein
    
8. Implantable biosensor and methods of use thereof
    
9. Use of Acacia Gum to isolate and preserve biological material
    
10. Direct encapsulation of biomacromolecules in surfactant templated mesoporous and nanoporous materials
     
11. Sensor protein and use thereof
     
12. Methods and reagents for the detection of antibodies to adenovirus
     
13. Method for depositing an enzyme on an electrically conductive substrate

Biosynthesis/Bioreactor

1. Methods and compositions for increasing replication capacity of an influenza virus
    
2. Mutant tyrosine repressor, a gene encoding the same, and a method for producing L-DOPA
    
3. Method for obtaining new life forms
    
4. Method of stripping genetically tagged biomolecules from porous solid ion exchange wafer
    
5. Transgenic plants used as a bioreactor system
    
6. Antibody composition-producing cell
    
7. Hydrogel functionalized with a polymerizable moiety and their uses as biosensors or bioreactors
    
8. Robust expression of a bioactive mammalian protein in chlamydomonas chloroplast
    
9. Microbial production of vitamin C
    
10. Process for the intracellular over-production of streptokinase using genetically engineered strain of E. coli
     
11. Process for producing human thrombin by gene modification technique
     
12. Gene encoding a nonribosomal peptide synthetase for the production of ramoplanin
     
13. Commercial production of insulin and insulin-like protein in plants
     
14. Bacterial host cell for the direct expression of peptides
     
15. Methods and compositions for increasing longevity and protein yield from a cell culture
     
16. Decision-making spectral bioreactor
     
17. Microreactor 
     
18. Placental stem cells
     
19. Cloning genes from Streptomyces cyaneogriseus subsp. Noncyanogenus for biosynthesis of antibiotics and methods of use
     
20. Secreted and transmembrane polypeptides and nucleic acids encoding the same
     
21. Production of urokinase in a three-dimensional cell culture
     
22. Enhanced secretion of a polypeptide by a microorganism
     
23. Hepatocyte bioreactor system for long term culture of functional hepatocyte spheroids
     
24. Metabolic engineering of viomycin biosynthesis
     
25. Genes encoding genetic stability, gene expression and folding proteins
     
26. Biosynthetic gene cluster for leptomycins
     
27. Device and a process for expansion of haemopoeitic stem cells for therapeutic use
     
28. Gene cluster for production of the enediyne antitumor antibiotic C-1027
     
29. Regulation of translation for recombinant protein production
     
30. Ex vivo generation of functional leukemia cells in a three-dimensional bioreactor
     
31. Method for biosynthesizing the serotonin derivatives in plants
     
32. Biomass generator
     
33. Process for the preparation of pseudomonic acid a antibiotic by microbiological method
     
34. Escherichia coli strain secreting human granulocyte colony stimulating factor (G-CSF)
     
35. Process for scaled-up production of recombinant proteins using transgenic plant suspension cultures
     
36. Method and apparatus for performing multiple processing steps on a sample in a single vessel
     
37. Production of human parathyroid hormone from microorganisms
     
38. Method for large scale production of virus antigen
     
39. Method of producing a polypeptide using oxaloacetate hydrolase deficient fungal host cells
     
40. Glycoconjugates and methods
     
41. Rifamycin biosynthesis gene cluster
     
42. Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor
     
43. Methods for efficient production of mammalian recombinant proteins
     
44. Transgenic animals as urinary bioreactors for the production of polypeptide in the urine, recombinant DNA construct for kidney-specific expression, and method of using same
     
45. Process for producing omega-9 highly unsaturated fatty acid and lipid containing the same
     
46. Methods and compositions for increasing protein yield from a cell culture

Blood-Brain Barrier

1. Methods and compositions for modulation of blood-neural barrier
    
2. Blood brain barrier device
    
3. Methods and compositions for targeting proteins across the blood brain barrier
    
4. Methods of transnasal transport/immunization with highly adaptable carriers
    
5. Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier
    
6. Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier
    
7. Molecules for transporting a compound across the blood-brain barrier
    
8. Hybrid proteins that migrate retrogradely and transynaptically into the CNS
    
9. Peptides carrying substances across the blood brain barrier
    
10. Amino acid composition with increased blood brain barrier permeability
     
11. Peripheral marker of blood brain barrier permeability
     
12. Microparticles for drug delivery across mucosa and the blood-brain barrier
     
13. Modulating the permeability of a physiological barrier with an agent that modulates tyrosine phosphorylation
     
    
14. Material for passage through the blood-brain barrier

Chemical/Drug, Synthesis/Processing/Isolation

1. Enhanced purification of antibodies and antibody fragments by apatite chromatography
    
2. Proteins with enhanced functionality and methods of making novel proteins using circular permutation
    
3. Crystallization of iodixanol using ultrasound
    
4. Post-translational modifications and Clostridial neurotoxins
    
5. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
    
6. Antibody purification by protein a and ion exchange chromatography
    
7. Processes for production of Hoodia plant extracts containing steroidal glycosides
    
8. Polishing steps used in multi-step protein purification processes
    
9. Trans-sialidases obtained from Trypanosoma congolense
    
10. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
     
11. Computer system for designing oligonucleotides used in biochemical methods
     
12. Low molecular weight extraction process
     
13. Colostral fractionation process
     
14. Animal product free media and processes for obtaining a botulinum toxin
     
15. Synthetic peptide, inhibitor to DNA viruses
     
16. Methods for preparing low molecular weight heparin with modified heparinase III
     
17. Screening of chemical compounds purified from biological sources
     
18. H. pylori fucosyltransferases
     
19. Method for isolation of silymarin from Sylibum marianum seeds
     
20. Peptide-forming enzyme gene
     
21. Method of obtaining biologically active collagen from skins of the salmonidae fish
     
22. Sulfur-modified zinc oxide
     
23. Lipopolysaccharide .alpha.-2,3 sialyltransferase of campylobacter jejuni and its uses
     
24. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
     
25. Manufacture and purification of cyclosporin A
     
26. Process for producing fat composition containing hydrophobic components of glycyrrhiza
     
27. Media for clostridium bacterium and processes for obtaining a clostridial toxin
     
28. Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia
     
29. Antiviral substances from plant cuticular and epicuticular material
     
30. Process for isolating genistin from mixtures of soy isoflavones
     
31. Peptides and nucleic acids derived from Eisenia foetida and the use thereof
     
32. Method for preparing steroids modified by yeast fermentation
     
33. Process of purifying vancomycin hydrochloride
     
34. Continuous process for modifying starch and its derivatives by branching enzymes
     
35. Product from starfish
     
36. Soluble recombinant botulinum toxin proteins
     
37. Process for protein extraction
     
38. Isolation, characterization, cloning and use of a mushroom lectin
     
39. Method of manufacturing polyamine composition
     
40. Macrolide solvates
     
41. Process for preparing antibacterial and antioxidant fraction from Seabuckthorn (Hippophae rhamnoides L.)
     
42. Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from Uncaria tomentosa and related plants
     
43. Antithrombin nucleotides and proteins from horn fly
     
44. Rifamycin biosynthesis gene cluster
     
45. Antigenic protein originating in malassezia
     
46. Method for extracting a compound from a ginseng spp. plant, ginseng or pseudo-ginseng
     
47. Methods of synthesizing cell-free protein
     
48. Process for the preparation of amylase inhibitor
     
49. Process of extracting nucleic acid and process of simultaneously carrying out extraction and purification of nucleic acid
     
50. Process for the production of tocotrienols
     
51. Compositions isolated from bovine tissues and methods for their use
     
52. Methods and compositions for extracting proteins from cells
     
53. Process for producing omega-9 highly unsaturated fatty acid and lipid containing the same
     
54. Method of purifying lantibiotics
     
55. Momordica cochinchinensis (Spreng.) .beta.-carotene and method
     
56. Solventless extraction process
     
57. Water soluble paclitaxel derivatives
     
58. Production of thebaine and oripavine
     
59. Process of obtaining compositions of stable lutein and lutein derivatives
     
60. Invaplex from gram negative bacteria, method of purification and methods of use
     
61. Recovery of isoflavones from soy molasses
     
62. Methods for isolating T. pallidum rare outer membrane proteins
     
63. Process for the preparation in pure form of the protease activating blood clotting factor VII, its proenzyme or a mixture of both proteins by means of ion-exchange chromatography
     
64. Recovery of isoflavones from soy molasses
     
65. Stable salts of S-adenosyl-l-methionine
     
66. Trans-somatics with gene transfer into mammary epithelial cells
     
67. Process for extracting polyphenolic antioxidants from purine-containing plants
     
68. Isolated and purified 12R-lipoxygenase protein and nucleic acids
     
69. Compositions and methods for their preparation from lepidium
     
70. Crude drug extracts, and methods for making and standardizing same
     
71. Process for the preparation of acidic lipase
     
72. Synthetic endogenous cannabinoids analogues and uses thereof
     
73. Method for selectively obtaining antioxidant rich extracts from citrus fruits
     
74. Process for synthesis of pure warfarin acid, warfarin alkali metal salts and corresponding clathrates
     
75. Method and apparatus for preparing taxol using supercritical fluid from source materials
     
76. Process for producing isoflavone aglycone-containing composition
     
77. Process for purifying human leukocyte interferon
    
    
78. Cannabinoid extraction method
    
    
79. Process for the extraction of valerian root
    
    
80. Antioxidant compositions extracted from olives and olive by-products
    
    
81. Sulfated hyaluronic acid and esters thereof
     
82. Immunomodulatory and antimicrobial materials, their preparation and use
     
    
83. Process for the isolation of compound scopoletin useful as nitric oxide synthesis inhibitor
     
84. Process for producing chitosan-glucan complexes, compounds producible therefrom and their use
     
    
85. Process for producing aromatic compounds by supercritical water treatment
     
86. Method for concentrating .beta.-glucan
     
    
87. Method for synthesis of proteins
     
    
88. Process for isolating and purifying viruses and sugars from plant sources
     
    
89. Transforming growth factor .beta. crystals
     
    
90. Antimicrobial agents isolated from aloe vera
     
    
91. Isolation and structural elucidation of the human cancer cell growth inhibitory compound denominated agelagalastatin
     
    
92. Methods and compositions for peptide synthesis
     
    
93. Process for preparing natural product derivatives from plants in a single step
     
    
94. Corn extract contraceptive
     
    
95. Family of peptides known as xenoxins
     
    
96. Manufacturing process of metoprolol
     
    
97. Fine cisplatin powder and process for the production thereof
     
    
98. Soy isoflavone concentrate process and product
     
    
99. Anhydrous crystals
     
    
100. Process for making a cyclodextrin
      
     
101. Process for the preparation of immunomodulatory polysaccharides from aloe
      
     
102. Preparation of lipid-nucleic acid particles using a solvent extraction and direct hydration method
      
     
103. Highly purified tocopheryl phosphate, process for producing the same, analytical method therefor and cosmetic
      
     
104. Antacid co-polymer of guanidine and polyethylenimine
      
     
105. Process for the crystallization from a linear or branched (C5-C6) alcohol or their mixtures of (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyy l)amino]-2,4,6-triiodo-1,3-benzendicarboxamide

Chemical/Biological Warfare, Protection

1. Method for detecting bacterial spores
    
2. Mycobacterium vaccae for down-regulation of the Th2 activity of the immune system
    
3. Reactive nanoparticles as destructive adsorbents for biological and chemical contamination
    
4. Modified red blood cell that has surface molecules that neutralize chemical agents

Chemistry, Assay/Immunoassay/Determination/Experimental Techniques/Biochip

1. Measurement of renal extraction fraction using contrast enhanced computed tomography
    
2. Viral diagnostic method and well for use in same
    
3. Elemental analysis of tagged biologically active materials
    
4. Antibodies specific to antigens of Bartonella henselae and use of these antigens in immunoassays
    
5. Magnetic fine particles having lower critical solution temperature
    
6. Assay for the separation and quantification of hemagglutinin antigens
    
7. Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)--based methods for drug and diagnostic development
    
8. High throughput pharmaceutical screening using drosophila
    
9. Assay for the separation and quantification of hemagglutinin antigens
    
10. Apparatus and method for measuring concentrations of molecules through a barrier
     
11. Nanoparticle composite-coated glass microspheres for use in bioassays
     
12. Solid supports functionalised with phosphorus dendrimers, method for preparing same and uses thereof
     
13. Antibody pair screening methods
     
14. Methods of using fluorescent pH indicators for intracellular assays
     
15. Method for measuring the content of a botulinum toxin in a formulation
     
16. Method for reducing influence of hemoglobin with albumin in an assay
     
17. Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins
     
18. Kits for detection of nucleic acids by invasive cleavage
     
19. Method for detecting intracellular cholesterol
     
20. Solventless extraction process
     
21. Directed microwave chemistry
     
22. Process for partitioning of proteins
     
23. Rapid assays for neurotransmitter transporters
     
24. Rapid and efficient capture of DNA from sample without using cell lysing reagent
     
25. Cytotoxin-based biological containment
     
26. Quantitative measurement method and quantitative measurement chip for target substance
     
27. Treatment of substrates for immobilizing biomolecules
     
28. High throughput screening of ligand binding to macromolecules using high resolution powder diffraction
     
29. Uncoupling of DNA insert propagation and expression of protein for phage display
     
30. Control of ph transitions during chromatography
     
31. Internal quality control
     
32. Vitamin D assay
     
33. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
     
34. Pretreatment kit for saliva and pretreatment method for saliva
     
35. Method for detecting an analyte by fluorescence
     
36. Direct adsorption scintillation assay for measuring enzyme activity and assaying biochemical processes
     
37. Immunoassay method
     
38. Methods and reagents to detect and characterize norwalk and related viruses
     
39. Method of detecting an antibody in a liquid sample
     
40. Methods for direct detection of individual methotrexate metabolites
     
41. Detection and quantitation of 8-OH-adenine using monoclonal antibodies
     
42. Method for quantifying cholesterol in high density lipoprotein
     
43. Method of preparing cow brain homogenate
     
44. Antigens embedded in thermoplastic
     
45. Quantitative assay of host cell DNA in a sample
     
46. Characterizing polypeptides through cleavage and mass spectrometry
     
47. Step agglutination immunoassay
     
48. Process for analyzing annexin-V in urine, and application thereof
     
49. Fluorescent capture assay for kinase activity employing an anti-phosphotyrosine antibody as both the capture agent and detecting agent
     
50. Homogeneous assay of vancomycin using a stable particle-vancomycin conjugate, a novel rate enhancer, and a novel dose response modulator
     
51. Methods for quantitative analysis of nucleic acid amplification reaction
     
52. Stabilization of particles and reduction of sample discordance in immunoassays using casein coating of particles
     
53. Assay for detecting, measuring and monitoring the activities and concentrations of proteins and methods of use thereof
     
54. Reagent preparation containing magnetic particles in tablet form
     
55. Microcolumn chromatographic immunoassays
     
56. Immunoassay method and kit
     
57. Antibodies to specific regions of cyclosporine related compounds
     
58. Specificity in the detection of anti-rubella IgM antibodies
     
59. Biosensor containing glucose dehydrogenase
     
60. Compositions and methods for monitoring the phosphorylation of natural binding partners
     
61. Expression of functional cytochrome P450 monooxygenase system in enterobacteria
     
62. Method for preparation and use of preservative-free immunoassay reagents
     
63. Stabilization of cardiac troponin I subunits and complexes
     
64. Immunoassay for measuring human C-peptide and kit therefor
     
65. Interference reduction by rheumatoid factors
     
66. Signal enhancement of bispecific antibody-polymer probe for immunoassay use
     
67. Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
     
68. Method of detecting an antibody in a liquid sample
    
    
69. 17867 a novel human aminopeptidase
    
    
70. Assays and probes with enzyme labels
    
    
71. NANBV diagnostics and vaccines
    
    
72. Fluorescent nanocrystal-labeled microspheres for fluorescence analyses
     
    
73. Heterogeneous assay for pyrophosphate
     
    
74. Fluorescent energy transfer ligand interaction assay on a lipid film
     
    
75. Heterogeneous assay for pyrophosphate detection
     
    
76. Method for detecting or quantifying carbohydrate containing compounds
     
    
77. Assays for screening for inhibitors of HIV
     
    
78. Method to detect proteins
     
    
79. Three-dimensional colorimetric assay assemblies
     
    
80. Method for stabilizing trypsin, method for increasing enzymatic activity of trypsin, and kit for measuring enzymatic activity of trypsin
     
    
81. Multiassay method for determining the concentrations of antigens and interferants
     
    
82. Stabilized coenzyme solutions and their use thereof for the determination of dehydrogenases or the substrate thereof in an alkaline medium
     
    
83. Chemical and pharmacological standardization of herbal extracts
     
    
84. Apparatus and method for kinetic analysis of the intraoperative assay for parathyroid hormone
     
    
85. Stabilization of proteins in solution
     
    
86. Arrangement and method of examining hydrophilic macromolecules in an aqueous solution

Chemistry, Adsorption

1. Attaching a biological molecule to a support surface

Chemistry, Cross-Linking

1. Crosslinking of hyaluronan solutions and nanofiberous membranes made therefrom
    
2. Blend, cross-linkable poly(propylene fumarate) for immobilization and controlled drug delivery
    
3. Process for cross-linking hyaluronic acid to polymers
    
4. Drug-loaded biological material chemically treated with genipin
    
5. Process for the preparation of a controlled release system
    
   
6. Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds
    
   
7. Medical devices comprising cross-linked hydrogels having improved mechanical properties
    
   
8. Method for control of functionality during cross-linking of hemoglobins
    
   
9. Controlled dissolution crosslinked protein crystals
    
   
10. Polyvinyl alcohol compositions prepared by crosslinking in a freezing step

Chemistry, Nucleic Acid/Protein/Polypeptides

1. Construction of diverse synthetic peptide and polypeptide libraries
    
2. Proteins with enhanced functionality and methods of making novel proteins using circular permutation
    
3. Polishing steps used in multi-step protein purification processes
    
4. Method for refolding a protein
    
5. Cleavage of nucleic acids
    
6. Drug design based on the structure of LTA.sub.4 hydrolase
    
7. Evolving new molecular function
    
8. Cysteine-containing peptide tag for site-specific conjugation of proteins
    
9. Methods for detection of a target nucleic acid by capture
    
10. Hedgehog fusion proteins
     
11. Methods for purifying protein
     
12. Stabilizing polypeptides which have been exposed to urea
     
13. Method of purifying nucleic acid using silver nanoparticles
     
14. Stabilized protein crystals, formulations comprising them and methods of making them
     
15. Directed microwave chemistry
     
16. Process for partitioning of proteins
     
17. Peptide-forming enzyme gene
     
18. Methods for structural analysis of proteins
     
19. PRO536 polypeptides
     
20. Rapid and efficient capture of DNA from sample without using cell lysing reagent
     
21. Method for separating and purifying a nucleic acid
     
22. Enhanced protein thermostability and temperature resistance
     
23. Secreted and transmembrane polypeptides and nucleic acids encoding the same
     
24. PRO1313 polypeptides
     
25. Peptides with enhanced stability to protease degradation
     
26. Random truncation and amplification of nucleic acid
     
27. Modified polypeptides stabilized in a desired conformation and methods for producing same
     
28. Biologically active metal-containing nucleic acids
     
29. Monomeric and dimeric fluorescent protein variants and methods for making same
     
30. Methods for purifying protein
     
31. Process for producing peptides by using in vitro transcription/translation system
     
32. Methods and compositions for protein expression and purification
     
33. Compositions and methods for labeling of nucleic acid molecules
     
34. Stabilized proteins
     
35. Method of protein purification
     
36. Method for purifying recombinant proteins expressed as insoluble aggregates
     
37. Emission ratiometric indicators of phosphorylation
     
38. Methods for detecting polymorphisms in nucleic acids
     
39. Complexity management of genomic DNA
     
40. Method of reconstituting nucleic acid molecules
     
41. Methods of synthesizing cell-free protein
     
42. Process of extracting nucleic acid and process of simultaneously carrying out extraction and purification of nucleic acid
     
43. Characterizing polypeptides through cleavage and mass spectrometry
     
44. Methods and compositions for extracting proteins from cells
     
45. Nanoparticles having oligonucleotides attached thereto and uses therefor
     
46. Methods for quantitative analysis of nucleic acid amplification reaction
     
47. Polymorphism analysis by nucleic and acid structure probing
     
48. Self assembling proteins
     
49. Nucleic acid isolation
     
50. Identification and expression of a novel kinesin motor protein
     
51. Method for determining the three-dimensional structure of a protein
     
52. Compositions and methods for monitoring the phosphorylation of natural binding partners
     
53. System and methods for the rapid isolation of nucleic acids

Chimeric Mammals

1. Chimeric mammals with human hematopoietic cells

Cryopreservation/Preservation, Biological Samples

1. Biological material and methods and solutions for preservation thereof
    
2. Method and preparations for stabilizing biological materials by drying methods without freezing
    
3. Method of reconstituting nucleic acid molecules
    
4. Method for the preservation of biologically-active material
    
5. Preservation of liquid biological samples
    
6. Sheets of cultured epithelial cells used for wound repair and their cryopreservation
    
7. Method and apparatus for cryopreservation

Chemistry, General

1. Systems and methods for the generation of crystalline polymorphs
    
2. Measurement and use of molecular interactions
    
3. Estimating the accuracy of molecular property models and predictions

Cytokine/Chemokine, Related Invention/Treatment

1. MU-1, member of the cytokine receptor family
    
2. IFN-.lamda. polypeptides and compositions
    
3. Compositions for detecting and treating diseases and conditions related to chemokine receptors
    
4. Cytokine zalpha11 ligand fusion proteins
    
5. Cytokine zalpha11 ligand fusion proteins
    
6. Cytokine zalpha11 ligand fusion proteins
    
7. Methods of inhibiting chemokine binding to chemokine receptors
    
8. Amended recombinant cells for the production and delivery of gamma interferon as an antiviral agent, adjuvant and vaccine accelerant
    
9. Chemokines mutants having improved oral bioavailability
    
10. Method of treatment using a cytokine able to bind IL-18BP to inhibit the activity of a second cytokine
     
11. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
     
12. CC chemokine receptor 5 DNA, new animal models and therapeutic agents for HIV infection
     
13. Therapeutic agents as cytokine antagonists and agonists
     
14. Antibodies to human 4-1BB
     
15. Chemokine alpha-2 antibodies
     
16. Method of determining cytokine dosage for myelosuppressive state
     
17. Modified cytokine
     
18. MCP-1 receptor antibodies
     
19. Antibodies to human chemokine beta-9
     
20. Method for administering a cytokine to the central nervous system and the lymphatic system
     
21. Cytokine antagonists for neurological and neuropsychiatric disorders
     
22. Chemokine receptor obtained from a CDNA library of fetal liver-spleen
     
23. Enhancing immune responses to genetic immunization by using a chemokine
     
24. Metalloproteinases
     
25. Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient
     
26. Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
     
27. Macrophage derived chemokine (MDC) and chemokine analogs and assay to identify modulators of MDC activity, and therapeutic uses for same
     
28. Class II cytokine receptor-7
     
29. Oromucosal cytokine compositions and uses thereof
     
30. Mammalian growth factor-7
     
31. Compositions and methods for modifying toxic effects of proteinaceous compounds
     
32. Receptor activator of NF-.kappa.B
     
33. Cytokine antagonists for the treatment of localized disorders
     
34. Adenoviral vectors encoding a cytokine and a conditionally lethal gene
     
35. Antibodies directed against trail
     
36. Feline cytokine protein
     
37. Chemokine binding protein and methods of use therefor
     
38. Inhibition of cytokine production
     
39. IL8 inhibitors
     
40. Cytokine antagonists for the treatment of sensorineural hearing loss
     
41. Highly purified cytokine activating factor and methods of use
     
42. Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
    
    
43. Use of cytokines and mitogens to inhibit pathological immune responses
    
    
44. Cytokine suppressive anti-inflammatory drug binding protein