Patent Classification
 

Disinfection/Cleaning/Buffer, Contact Lens

1. Use of inorganic nanoparticles to stabilize hydrogen peroxide solutions
    
2. Two-part disinfecting systems and compositions and methods relating thereto
    
3. Contact lens and opthalmic solutions
    
4. Method of disinfecting contact lens and disinfecting liquid for the method
    
5. Ophthalmic and contact lens solutions
    
6. Contact lens cleaning compositions
    
7. Bactericide against vancomycin resistant enterococcus
   
   
8. Ophthalmic anti-allergy compositions suitable for use with contact lenses
   
   
9. Compositions and methods to disinfect contact lenses
    
10. Multi-purpose contact lens care compositions
     
    
11. Bis-amido polybiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions
     
    
12. Device for catalytically dissolving hydrogen peroxide
     
    
13. Method and composition for rewetting contact lenses and relieving eye dryness
     
    
14. Agent for contact lenses
     
    
15. Enzyme compositions and methods for contact lens cleaning
     
    
16. Stable active-ingredient combination for the disinfection and cleaning of contact lenses, and packing and process for the preparation thereof
     
    
17. Liquid for contact lenses
     
    
18. Mutli-purpose contact lens care compositions
     
    
19. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias
     
    
20. Hydrogen peroxide destroying compositions and methods of using same

Drug Bioavailability/Pharmacokinetic/Metabolism

1. Bioequivalence evaluation method of evaluating bioequivalence of a generic drug to the corresponding original drug
    
2. Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
    
3. Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
    
4. Method for increasing bioavailability of lipophilic bioactive compounds
    
5. Bioavailability/bioefficacy enhancing activity of Cuminum cyminum and extracts and fractions thereof
    
6. Fc-erythropoietin fusion protein with improved pharmacokinetics
    
7. Method to enhance drug release from a drug-releasing material
    
8. Method of measuring binding site on plasma protein of plasma protein-binding drug and method of measuring plasma protein mutation
    
9. Pharmaceutical composition for oral use with improved absorption
    
10. Methods for evaluating the ability to metabolize pharmaceuticals
     
11. Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
     
12. Method and apparatus for assaying a drug candidate to estimate a pharmacokinetic parameter associated therewith
     
13. Water soluble paclitaxel derivatives
     
14. Method for increasing the bioavailability of metaxalone
    
    
15. Intraconazole exhibiting an improved solubility, a method of preparing the same and a pharmaceutical composition for oral administration comprising the same
    
    
16. Methods for determining therapeutic index from gene expression profiles
     
    
17. Method and formulation for increasing the bioavailability of poorly water-soluble drugs
     
    
18. Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
     
    
19. Propyl gallate to increase bioavailability of orally administered pharmaceutical compounds

Drug Discovery/Screening

1. Target protein and target gene in drug designing and screening method
    
2. Methods for identifying compounds for the treatment of type 1 diabetes
    
3. Glycodendrimers having biological activity
    
4. Determining the capability of a test compound to affect solid tumor stem cells
    
5. Methods for measuring rates of reverse cholesterol transport in vivo, as an index of anti-atherogenesis
    
6. Identification of pharmacophores from co-crystals of spleen tyrosine kinase (SYK) and SYK ligands
    
7. Transgenic mouse for screening and for studies of the pharmacodynamics and pharmacokinetics of ligands acting on the oestrogen receptor and its intracellular receptors, and method for the preparation thereof
    
8. Systems and method for discovery and analysis of markers
    
9. Methods of screening an agent for an activity in an isolated eye of a teleost
    
10. Method of treating mouse carrying human hepatocytes
     
11. Method for rapid screening of bacterial transformants and novel simian adenovirus proteins
     
12. Screening methods for identifying viral proteins with interferon antagonizing functions and potential antiviral agents
     
13. Automatable artificial immune system (AIS)
     
14. Methods of screening agents for activity using teleosts
     
15. Method for designing a potential inhibitor of glutathione-aldehyde conjugate binding to aldose reductase
     
16. Methods of screening agents for activity using teleosts
     
17. Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)--based methods for drug and diagnostic development
     
18. Method for screening agents for the treatment of diabetes
     
19. Structure-based hepatitis C virus drug design
     
20. Drug design based on the structure of LTA.sub.4 hydrolase
     
21. Methods for assessing efficacy of chemotherapeutic agents
     
22. SKN-1 and GSK-3 genes and proteins
     
23. Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor
     
24. TWEAK receptor
     
25. Genetic screen for bioactive peptides
     
26. Epitope directed selection of antibodies to murine tissue factor
     
27. Skin substitutes for irritancy testing
     
28. Screening for West Nile Virus antiviral therapy 
     
29. Methods of inhibiting chemokine binding to chemokine receptors
     
30. Methods of screening agents for activity using teleosts
     
31. Transformed cell with enhanced sensitivity to antifungal compound and use thereof
     
32. Systems and methods for screening pharmaceutical chemicals
     
33. Securin is required for chromosomal stability in human cells
     
34. Population of Hoxb8 mutants and uses in identifying agents for treating repetitive behaviors
     
35. Exhaustive selection of RNA aptamers against complex targets
     
36. System to detect inducible translocation
     
37. Methods of screening agents for activity using teleosts
     
38. Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
     
39. Method for screening anti-bacterial agents
     
40. Methods for screening compounds for proarrhythmic risk and antiarrhythmic efficacy
     
41. Isolated proteins from a traditional Chinese medicine Yuzhu and use thereof
     
42. Methods of identifying therapeutic compounds in a genetically defined setting
     
43. Conus californicus neurotoxins
     
44. High-throughput assay for virus entry and drug screening
     
45. Hepatocytes for therapy and drug screening made from embryonic stem cells
     
46. Methods for screening compounds that modulate lipid metabolism
     
47. Methods for detecting DNA damage and screening for cancer therapeutics
     
48. Simultaneous determination of cell proliferation inhibition activity and toxicity
     
49. Binding domains between presenilins and their substrates as targets for drug screening
     
50. Drug sensitivity measuring method
     
51. Methods of screening compounds useful for prevention of infection or pathogenicity
     
52. Histamine receptor H3 modified transgenic mice
     
53. Marine actinomycete taxon for drug and fermentation product discovery
     
54. Sodium-independent small neutral amino acid transporter transporting L- and D-amino acids
     
55. Method and screening candidate compounds for drug against tumor
     
56. Display of receptors and analysis of binding interactions and drug libraries
     
57. Screening methods used to identify compounds that modulate a response of a cell to ultraviolet radiation exposure
     
58. Compositions and methods involving an essential Staphylococcus aureus gene and its encoded protein
     
59. Transgenic mouse expressing constitutively active hydrocarbon receptor
     
60. G-protein coupled receptors
     
61. Methods and compositions for the identification of antibiotics that are not susceptible to antibiotic resistance
     
62. Methods for screening compounds that bind human COE-2
     
63. Production of cultured human mast cells and basophils for high throughput small molecule drug discovery
     
64. Methods for screening GABA-modulatory compounds for specified pharmacological activities
     
65. Depression gene
     
66. Skeletal cell model to screen anti-diabetic compounds
    
 
67. Method of evaluating drug efficacy and toxicity
     
68. Cells for drug discovery
     
69. Fetally expressed gene as a human colon cancer marker
     
70. Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
     
71. Method for identifying active anti apoptosis compounds
     
72. Isoforms of the human vitamin D receptor
     
73. Antibodies that recognize and bind phosphorylated human glucocorticoid receptor and methods of using same
     
74. Method for screening compounds inhibiting signal transduction through inflammatory cytokines
     
75. Cells for drug discovery
     
76. Methods for designing specific ion channel blockers
     
77. Drug screening using a proline-rich nuclear receptor co-regulatory protein/nuclear receptor co-expression system
     
78. Screening methods for compounds useful in the regulation of cell proliferation
     
79. Methods and compositions for inhibition of RNA splicing
     
80. Methods for identifying compounds that inhibit CD38 activity
     
81. Genes and polynucleotides associated with ultraviolet radiation-mediated skin damage and uses thereof
     
82. Transgenic animals having a modified glycoprotein V gene
     
83. Methods for screening compounds active on neurons
     
84. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
     
85. Medicine response assay in respiratory disease
     
86. Methods for identifying polypeptide factors interacting with RNA
     
87. Transgenic mice comprising a constitutively-activated MEK5 and exhibiting cardiac hypertrophy and dilated cardiomyopathy
     
88. Methods to screen for antibiotic agents and their use in treatment of opportunistic infections
     
89. Screening for drugs that affect TNF receptor releasing enzyme
     
90. Multiparameter FACS assays to detect alterations in exocytosis
     
91. Virus derived antimicrobial peptides
     
92. Method for ascertaining the quality of herbs
     
93. Autoregulatory system for validating microbial genes as possible antimicrobial targets using a tetracycline-controllable element
     
94. System for cell-based screening
     
95. Methods and compositions for screening for angiogenesis modulating compounds
     
96. Method for screening compounds for anti-inflammatory activity
     
97. Genetic screening methods
     
98. Variation in drug response related to polymorphisms in the .beta.2-adrenergic receptor
     
99. Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor
     
100. Method of screening for pharmaceuticals by detecting cross talk between intracellular signals and intranuclear receptors
      
101. Methods for the identification of inhibitors of asparagine synthase as antibiotics
      
102. Method for identifying validated target and assay combination for drug development
      
103. Method of assaying modulators of hypertension
      
104. Methods of screening for compounds that bind to activin receptor
      
105. Microorganisms and assays for the identification of antibiotics
      
106. Method of observing vasculogenesis in vitro using cultured allantois
      
107. Process for determination of the activity of a substance using an in vitro functional test
      
108. Stabilized bioactive peptides and methods of identification, synthesis and use
      
109. Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules
      
110. Mouse mammary tumor lines expressing estrogen and progesterone receptors
      
111. Methods for the identification of inhibitors of threonine synthase as antibiotics
      
112. Methods for identifying contraceptive compounds
      
113. Mass1 gene, a target for anticonvulsant drug development
      
114. Compound screening method
      
115. Transgenic mice containing BMP gene disruptions
      
116. Vectors encoding HCN channels and MiRP1
      
117. Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases
      
118. High throughput screening assays using fatty acid synthetic enzymes
      
119. Human cell line showing stable expression of cytochromes P450
      
120. Method to enhance and/or prolong the effects of a primary challenge to a responsive system with a secondary challenge
      
121. System and method for evaluating agents which prevent oxidative damage
      
122. Knockout mouse for the tumor suppressor gene ANX7
      
123. Methods of screening novel agents for use in cancer therapy and prevention
      
124. Identification of drugs and drug targets by detection of the stress response
      
125. Methods for the identification of inhibitors of histidinol-phosphate as antibiotics
      
126. Method of screening for non-steroidal neuropsychiatric agents
      
127. Methods for the identification of antimicrobial compounds
      
128. System and method for investigating the effect of chemical and other factors on cell movement
      
129. Genes identified as required for proliferation in Escherichia coli
      
130. Method of determining evolutionary potential of mutant resistance genes and use thereof to screen for drug efficacy
      
131. Methods for identifying cardiovascular agents
      
132. Methods for the identification of inhibitors of 5-aminolevulinate synthase as antibiotics
      
133. Neuropeptides originating in scorpion
      
134. Method for selective inactivation of viral replication
      
135. Methods for measuring the metabolism of and screening for drugs in isolated hearts
      
136. Transgenic mice exhibiting increased susceptibility to seizures
      
137. Methods for screening compound libraries
      
138. Reporter gene based method for the screening of anti-tuberculosis drugs by using essential and regulatory genes of mycobacteria as drug target
      
139. Methods for the identification of inhibitors of homocitrate synthase as antibiotics
      
140. Method for selective inactivation of viral replication
      
141. Use of drosophila melanogaster as a model for screening psychostimulant plant material
      
142. Screening assays for compounds that cause apoptosis and related compounds
      
143. Selection of contrast agent drug from a combinatorial library
      
144. Identification of compound-protein interactions using libraries of protein-nucleic acid fusion molecules
      
145. Method of screening anti-mycobacterial molecules
      
146. Cell-based drug screens for regulators of gene expression
      
147. Process for the preparation of immunogens or diagnostic reagents, and immunogens or diagnostic reagents thereby obtainable
      
148. Crystalline farnesyl protein transferase compositions and methods for use
      
149. High throughput sarcomeric assay
      
150. Drug screening and diagnosis based on paracrine tubular renin-angiotensin system
      
151. Analgesic screening method and composition
      
152. Human xenografts for microbicide testing and anatomical modeling
      
153. Method for identifying validated target and assay combinations for drug development
      
154. Uses for DNA structure-specific recognition protein
      
155. Method for screening agonist or antagonist of the maxadilan receptor participating in vasodilating action, and compound found by the method
      
156. Methods of screening compounds useful for prevention of infection or pathogenicity
      
157. Method for judging effectiveness of drug having protease inhibitory activity
      
158. Method for selecting compounds for treating ischemia-related cellular damage
     
     
159. Classification of biological agents according to the spectral density signature of evoked changes in cellular electric potential
     
     
160. Screening of molecules that inhibit human phosphodiesterase 4A produced by non-recombinant cell lines
     
     
161. Prokaryotic polynucleotides polypeptides and their uses
     
     
162. Screening novel human phosphodiesterase IV isozymes for compounds which modify their enzymatic activity
      
     
163. Screening method for the identification of plants possessing anti-microbial activity and tolerance to abiotic stresses

Drug Interaction

1. Methods and products related to metabolic interactions in disease
    
2. Drug delivery system for averting pharmacokinetic drug interaction and method thereof

Drug Resistance

1. Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
    
2. Methods and compositions for overcoming resistance to biologic and chemotherapy
    
3. Agent for treatment of cisplatin-resistant cancer
    
4. Compounds and methods for modulating cell-adhesion mediated drug resistance
    
5. Method and system for predicting resistance of a disease to a therapeutic agent using a neural network
    
6. Methods of monitoring HIV drug resistance
    
7. Compounds and methods for modulating cell-adhesion mediated drug resistance
    
8. Method and kit for detecting resistance to antiviral drugs
    
9. Method of determining evolutionary potential of mutant resistance genes and use thereof to screen for drug efficacy
    
10. Methods of reducing microbial resistance to drugs
     
11. Methods for detecting and reversing resistance to macrocyclic lactone compounds
     
12. Compounds for reversing drug resistance

Drug Responses

1. Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments
    
2. Method for monitoring early treatment response
    
3. Predicting response to chemotherapy using gene expression markers
    
4. Method of evaluating pharmacological effects of medicine
    
5. Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
    
6. Sensitivity test to predict efficacy of anti-cancer therapies
    
7. Methods of classifying drug responsiveness using multiparameter analysis
    
8. Method for monitoring early treatment response
    
9. Method of determining therapeutic activity and/or possible side-effects of a medicament
    
10. Cell-free assay using oncogene-induced apoptosis to identify inhibitors of apoptosis in drug-resistant cells
     
11. Methods for determining therapeutic index from gene expression profiles

Drug/Chemical Stability

1. Formulations for coated microprojections containing non-volatile counterions
    
2. Use of oligomers and polymers for drug solubilization, stabilization, and delivery
    
3. Stable pharmaceutical compositions, processes for making the same and methods of their use
    
4. Stable compositions of S-adenosyl-l-methionine with dextran
    
5. Use of inorganic nanoparticles to stabilize hydrogen peroxide solutions
    
6. Minimization of drug oxidation in drug irradiated excipients formulations
    
7. Enhanced protein thermostability and temperature resistance
    
8. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
    
9. Storage stable powder compositions of interleukin-4 receptor
    
10. Method of stabilizing reduced coenzyme Q.sub.10 and method of acidic crystallization
     
11. Stabilization of enzymes
     
12. Stabilized bioactive peptides and methods of identification, synthesis and use
     
13. Storage stable thyroxine active drug formulations and methods for their production
     
14. Stabilization of quinapril using magnesium oxide
     
15. Erythropoietin solution preparation
     
16. Stabilization of cardiac troponin I subunits and complexes
     
17. Artemisinins with improved stability and bioavailability for therapeutic drug development and application
     
18. Glycoprotein matrix compositions and methods related thereto
     
19. Storage stable thyroxine active drug formulations and methods for their production
     
20. Stabilized silver-ion amine complex compositions and methods
     
21. Ultraviolet-screening patch
     
22. Long-term stabilized formulations
     
23. Stable insulin formulations
     
24. Stable pharmaceutical compositions without a stabilizer
     
25. Microparticle protection of therapeutic agents
     
26. Glycoprotein matrix compositions and methods related thereto
     
27. Stabilization of solid thyroid drug formulations
     
28. Stabilization of ascorbic acid, ascorbic acid derivatives and/or extracts containing ascorbic acid for topical use
     
29. Stabilized aspirin compositions and method of preparation for oral and topical use
     
30. Stabilizing compositions comprising at least two anionic associative polymers, their use for stabilization of non-solid compositions, and compositions comprising at least one stabilizing composition
     
31. Inhibiting oxidative degradation of pharmaceutical formulations
     
32. Process for the stabilization of proteins in complex mixtures during their storage in aqueous solvents
     
33. Thermodynamically stable modification of 1-(4-carbazolyl-oxy-3[2-(2-methoxyphenoxy)-ethylamino]-2-propanol process for its preparation and pharmaceutical compositions containing it
     
34. Stable shaped particles of crystalline organic compounds
     
35. Stabilized thyroxine compounds
     
36. Stabilized cefuroxime axetil
     
37. Cyclodextrin stabilized pharmaceutical compositions of bupropion hydrochloride
     
38. Inhibiting oxidative degradation of pharmaceutical formulations
     
39. Method for increasing the serum half-life of a biologically active molecule
     
40. Stabilization of quinapril using magnesium oxide
     
41. Method for preparing ultraviolet radiation-absorbing compositions
    
    
42. Stabilization of photosensitive materials
    
    
43. Oral pharmaceutical preparation embedded in an oily matrix and methods of making the same
     
    
44. Process for stabilizing proteins
     
    
45. Stabilization of vitamin C
     
    
46. Stable calcitriol solution for packaging into vials
     
    
47. Stable transglutaminase preparations and processes for their production
     
    
48. Stabilized thyroxine medications
     
    
49. Stabilizing vitamin A derivatives by encapsulation in lipid vesicles formed with alkylammonium fatty acid salts
     
    
50. Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
     
    
51. Stabilized aspirin compositions and method of preparation for oral and topical use
     
    
52. Stabilized insulin compositions
     
    
53. Process for determining the phototoxicity and/or photosensitivity of substances or mixtures thereof, and uses thereof
     
    
54. Stabilized pharmaceutical compositions
     
    
55. Stable glycerine iodine concentrate compositions
     
    
56. Stable mitoxantrone solutions
     
    
57. Pharmaceutical composition which is stable during storage and contains a thymus extract
     
    
58. Stabilization of proteins in solution
     
    
59. Polar drug of prodrug compositions with extended shelf-life storage and a method of making thereof
     
    
60. Stable compositions containing N-propargyl-1-aminoindan
     
    
61. Water-soluble anti-oxidation agents
     
    
62. Natural antioxidant compositions, method for obtaining same and cosmetic, pharmaceutical and nutritional formulations thereof
     
    
63. Stabilized ascorbic acid, composition, and method of use
     
    
64. Stabilizing formulation for NGF
     
    
65. Sunscreen formulation with avobenzone and method for stabilizing sunscreen formulation which contains avobenzone
     
    
66. Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery
     
    
67. Bactericidal/permeability-increasing protein (BPI) compositions
     
    
68. Cyanamide aqueous solution
     
    
69. Stabilizers for lyophilized mumps vaccines
     
    
70. Process for stabilizing levogyre ascorbic acid (LAA), a stable aqueous LAA composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment
     
    
71. Stable hydrates of a cephalosporin chloride salt
     
    
72. Stable liquid paracetamol compositions, and method for preparing same
     
    
73. Stable preparation for the treatment of blood coagulation disorders
     
    
74. Crystalline trimetrexate salts and the process for making the same
     
    
75. Stabilized pharmaceutical compositions containing dobutamine
     
    
76. Stable solution of zinc ions and bicarbonate and/or carbonate ions
     
    
77. Storage-stable prostaglandin compositions
     
    
78. Method and compositions for solubilization and stabilization of polypeptides, especially proteins
     
    
79. Method of stabilizing pharmaceutical preparations comprising digestive enzyme mixtures
     
    
80. Cochleate delivery vehicles
     
    
81. Drug-resin complexes stabilized by chelating agents
     
    
82. Pharmaceutical formulation
     
    
83. Cilansetron pharmaceutical preparation stabilized against racemization
     
    
84. Pharmaceutical compositions of uridine triphosphate
     
    
85. Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer
     
    
86. Storage-stable drug form

Drug/Chemical Toxicity/Toxicology/Immunogenicity/Side Effect

1. Identifying organ damage
    
2. Method of predicting phospolipidosis inducing properties of a substance
    
3. Method and system for analyzing drug adverse effects
    
4. Risk assessment for adverse drug reactions
    
5. Method for graphically depicting drug adverse effect risks
    
6. Activation of peptide prodrugs by hK2
    
7. Methods for identifying and monitoring drug side effects
    
8. Compositions and methods for modifying toxic effects of proteinaceous compounds
    
9. Method of screening for drug hypersensitivity reaction
    
10. Method and system for analyzing drug adverse effects
     
11. Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor
     
12. Methods and compositions for determining risk of treatment toxicity
     
13. Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy
     
14. Methods for determining renal toxins
     
15. Molecular toxicology modeling
     
16. Method of treating side effects induced by therapeutic agents
     
17. Method of evaluating drug efficacy and toxicity
     
18. Hepatocurative effect of emblica officinalis against CYP 450 bio-activation hepatotoxicity of drugs
     
19. Propagation of human hepatocytes in non-human animals
     
20. Combating side-effects
     
21. Reducing the immunogenicity of fusion proteins
     
22. Delivery of a therapeutic agent in a formulation for reduced toxicity
     
23. Cytotoxicity assay
     
24. Method of determining therapeutic activity and/or possible side-effects of a medicament
     
25. Antibiotic sensitivity testing
     
26. In vivo high throughput toxicology screening method
     
27. Methods for determining toxicity reversing agents
     
28. Method for assessing genotoxicity of a compound
     
29. Detoxication of active pharmaceutical substances using cyclodextrine oligomers
     
30. Compositions and methods for modifying toxic effects of proteinaceous compounds
     
31. Genetic markers of toxicity preparation and uses
     
32. Method for testing the toxicity of chemical substances using gastropods
     
33. Methods of preparing low-toxicity drug-lipid complexes
    
    
34. Toxicological response markers
    
    
35. Process for determining the phototoxicity and/or photosensitivity of substances or mixtures thereof, and uses thereof
     
    
36. Acetaminophen composition with reduced liver toxicity

Equipment, Testing/Technique, Microscope

1. System and method for enhancing microscope images of tissue using citric acid and agents of the like
    
2. Method and apparatus for creating a virtual microscope slide

Genetic Engineering/Stem Cells

1. Methods and compositions for activating regenerative stem cells from bone marrow
    
2. Systems and methods for making hepatocytes from extrahepatic somatic stem cells and use thereof
    
3. Method of producing region-specific neurons from human neuronal stem cells
    
4. Passaged neural stem cell-derived neuronal networks as sensing elements for detection of environmental threats
    
5. Liver stem cell
    
6. Antibody that binds human eosinophil-derived basic protein
    
7. Methods for in vitro expansion of hematopoietic stem cells
    
8. Swine multipotent adult progenitor cells
    
9. Methods for obtaining adult human olfactory progenitor cells
    
10. Combinations of human proteins to enhance viability of transplanted stem cells and progenitor cells
     
11. Methods of controlling cell differentiation and growth using a fusion protein and a drug
     
12. Isolation and characterization of muscle regenerating cells
     
13. Methods of obtaining neural stem cells
     
14. Method for transdifferentiating mesenchymal stem cells into neuronal cells
     
15. Method of growing stem cells on a membrane containing projections and grooves
     
16. Systems and methods for treating patients with processed lipoaspirate cells
     
17. Differentiation of bone marrow stromal cells to neural cells or skeletal muscle cells by introduction of notch gene
     
18. MiRNA molecules isolated from human embryonic stem cell
     
19. Embryonic stem cell self maintenance and renewal reporter
     
20. Cultures of GFAP.sup.+ nestin.sup.+ cells that differentiate to neurons
     
21. Isolated placental perfusate and placental cells isolated therefrom
     
22. Combined regulation of neural cell production
     
23. Method for processing and using adipose-derived stem cells
     
24. Method of forming mesenchymal stem cells from embryonic stem cells
     
25. Method for differentiating primate embryonic stem cell into vascular cell
     
26. Multipotent amniotic fetal stem cells
     
27. Use of TGF beta superfamily antagonists to make dopaminergic neurons from embryonic stem cells
     
28. Peripheralization of hematopoietic stem cells
     
29. Stable neural stem cell line methods
     
30. Antibodies for identifying and/or isolating at least one cell population which is selected from the group comprising haematopoietic stem cells, neuronal stem cells, neuronal precursor cells, mesenchymal stem cells and mesenchymal precursor cells
     
31. Method of generating human retinal progenitors from embryonic stem cells
     
32. Method of producing cardiomyocytes from mesenchymal stem cells
     
33. Adult stem cell lines
     
34. Method of stimulating stem cells
     
35. Non human animals with human-glial chimeric brains
     
36. Cardiac muscle regeneration using mesenchymal stem cells
     
37. Systems and methods for treating patients with processed lipoaspirate cells
     
38. Transgenic rats and spermatogonial stem cells
     
39. Enhanced growth of adult stem cells with Dkk-1
     
40. Method for producing dendritic cells
     
41. Method for enhancing keratinocyte stem cells
     
42. Placental stem cells
     
43. Transgenic non-human mammals as models for human pathologies of stem cell origin
     
44. Direct differentiation method for making cardiomyocytes from human embryonic stem cells
     
45. Stem cells and their use in transplantation
     
46. Methods for identifying stem cells based on nuclear morphotypes
     
47. Methods for use of MPL ligands with primitive human stem cells
     
48. Human embryonic stem cells having genetic modifications
     
49. Culture system for rapid expansion of human embryonic stem cells
     
50. Stem cell-specific promoters and their use
     
51. Prolactin induced increase in neural stem cell numbers
     
52. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (PACAP)
     
53. Loop peptide and TGF.alpha. for stimulating stem cell proliferation and migration
     
54. Methods of cancer therapy targeted against a cancer stem line
     
55. Multipotent neural stem cell compositions
     
56. Endoderm cells from human embryonic stem cells
     
57. Methods of controlling proliferation and differentiation of stem and progenitor cells
     
58. Growth factor therapy mobilization of stem cells into the peripheral blood
     
59. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
     
60. Hepatocytes for therapy and drug screening made from embryonic stem cells
     
61. Differentiation of bone marrow cells into neuronal cells and uses therefor
     
62. Use of oxidized lipoproteins for differentiation of precursor cells into mature dendritic cells
     
63. Method of generating neurons from stem cells and medium for culturing stem cells
     
64. Method for producing dendritic cells
     
65. Regulation of cytotrophoblast cell differentiation and cell migration
     
66. Stem cells that transform to beating cardiomyocytes
     
67. Clonal cultures of primate embryonic stem cells
     
68. Genome mutation by intron insertion into an embryonic stem cell genome
     
69. Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway
     
70. Neural stem cells and use thereof for brain tumor therapy
     
71. Device and a process for expansion of haemopoeitic stem cells for therapeutic use
     
72. Composite antibodies of humanized human subgroup IV light chain capable of binding to TAG-72
     
73. Promoter and plasmid system for genetic engineering
     
74. Targeted system for removing tumor cells from cell populations
     
75. Differentiation of whole bone marrow
     
76. Stimulator of stem cell division
     
77. Process for the depletion or removal of endotoxins
     
78. Multipotent neural stem cell cDNA libraries
     
79. Antigen presenting mesenchymal stem cells
     
80. Hematopoietic cell composition for use in transplantation
     
81. Tyrosine recombinase for genetic engineering
     
82. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
     
83. Hematopoietic stem cell proliferating agents
     
84. Method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom, and materials and methods using same
     
85. Implanting neural progenitor cells derived for human embryonic stem cells
     
86. Intein mediated peptide ligation
     
87. Universal stem cells
     
88. Methods of controlling proliferation and differentiation of stem and progenitor cells
     
89. Gene transfer in chicken bursal stem cells
     
90. Methods of creating constructs useful for introducing sequences into embryonic stem cells
     
91. Relationship of ABC transport proteins with hematopoietic stem cells and methods of use thereof
     
92. Lineage specific cells and progenitor cells
     
93. Human embryonic stem cells derived from frozen-thawed embryo
     
94. Medium containing flt3 ligand for culturing hematophoietic cells
     
95. Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor
     
96. Gene delivery vectors with cell type specificity for mesenchymal stem cells
     
97. Composition comprising multipotent neural stem cells for generation of hematopoietic cells
     
98. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
     
99. Liver stem cell
     
100. Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
      
101. Method to determine an engrafting cell dose of hematopoietic stem cell transplant units
      
102. Genetically modified fibroblast cells
      
103. Production of tyrosine hydroxylase positive neurons
      
104. Modulation of primary stem cell differentiation using an insulin-like growth factor binding protein
      
105. Method for the isolation of stem cells by immuno-labeling with HLA/MHC gene product marker
      
106. Cardiac-cell specific enhancer elements and uses thereof
      
107. Method for enhancing stem cell trafficking
      
108. Discovery, localization, harvest, and propagation of an FGF2 and BDNF-responsive population of neural and neuronal progenitor cells in the adult human forebrain
      
109. Treatment of disorders by implanting stem cells and/or progeny thereof into gastrointestinal organs
      
110. Method for maintenance and propagation of germline stem cells using members of the TFG-.beta. family of growth factors
      
111. Sequence and method for genetic engineering of proteins with cell membrane translocating activity
      
112. Stem cells bearing an FGF receptor on the cell surface
      
113. Culturing pancreatic stem cells having a specified, intermediate stage of development
      
114. Methods and compositions for transforming dendritic cells and activating T cells
      
115. Gene switches
      
116. Directed evolution of microorganisms
      
117. Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures
      
118. Mutacin I biosynthesis genes and proteins
      
119. Engraftable human neural stem cells
      
120. Therapeutic uses for mesenchymal stromal cells
      
121. cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
      
122. Methods for use of delivery composition for expanding, activating, committing or mobilizing one or more pluripotent, self-renewing and committed stem cells
      
123. Reconstructed laminae of human epithelium corneae and method of producing the same
      
124. Gene transcription and ionizing radiation: methods and compositions
      
125. Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
      
126. Differentiation of human embryonic germ cells
      
127. Non-myeloablative/lymphoablative conditioning regimen to induce patient anti-donor unresponsiveness in stem cell transplantation
      
128. Methods and reagents for facilitating transcription
      
129. Neural transplantation using proliferated multipotent neural stem cells and their progeny
      
130. Antibody compositions for preparing enriched dendritic cell preparations
      
131. In vitro sorting method
      
132. Method for selective engraftment of drug-resistant hematopoietic stem cells
      
133. Method of producing human IFN-.alpha. using sendai virus-infected hematopoietic stem cells
      
134. Transcriptional inhibitor protein and the encoding DNA
      
135. Stimulation of cell proliferation by glycosylated cystatin C
      
136. Method and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules
     
     
137. Genetic engineering of cells to enhance healing and tissue regeneration
     
     
138. Method for transplantation of hemopoietic stem cells
     
     
139. Ligands that modulate differentiation of mesenchymal stem cells
     
     
140. Nucleic acid construct for the cell cycle regulated expression of structural genes
     
     
141. Hypoxia mediated neurogenesis
     
     
142. Human growth hormone to stimulate hematopoiesis and immune reconstitution after hematopoietic stem cell transplantation in humans
     
     
143. Potent genetic switch allowing regulated gene expression in eukaryotic cells
      
     
144. Differentiation-suppressive polypeptide
      
145. Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
      
     
146. DNA polymerase-related factors
      
     
147. Methods for use of Mpl ligands with primitive human stem cells
      
     
148. Method of enhancing the delivery of nucleic acids using silica nanoparticles
      
     
149. Nucleic acids containing modified human immunodeficiency virus genomes devoid of long terminal repeats encoding non-infectious, replication-deficient, immunogenic retrovirus-like particles
      
     
150. Use of a non-mammalian DNA virus to express an exogenous gene in a mammalian cell
      
     
151. Method for homing hematopoietic stem cells to bone marrow stromal cells
      
     
152. Expression monitoring of downstream genes in the BRCA1 pathway
      
     
153. Two-phase system for the production and presentation of foreign antigens in hybrid live vaccines
      
     
154. Regulation of hematopoietic stem cell differentiation by the use of human mesenchymal stem cells
      
     
155. Sequence and method for genetic engineering of proteins with cell membrane translocating activity
      
     
156. Production of megakaryocytes by the use of human mesenchymal stem cells
      
     
157. 1gG /transferrin receptor fusion protein
      
     
158. Gene expression in mammalian cells
      
     
159. Oral immunization with transgenic plants
      
     
160. Mouse embryonic stem cell lines
      
     
161. Genetically engineered mice containing alterations in the genes encoding retinoic acid receptor proteins

Genomics Research, Amplification

1. Methods and kits for amplification of RNA sequences using composite primers
    
2. Headloop DNA amplification
    
3. Amplification of DNA in a hairpin structure, and applications
    
4. Method for generating amplified RNA
    
5. Gene amplification methods
    
6. Single-primer nucleic acid amplification methods
    
7. Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations
    
8. Selective genome amplification
    
9. Methods and kits for amplification of RNA sequences using composite primers
    
10. Amplification of RNA sequences using composite RNA-DNA primers and strand displacement
     
11. Method for assaying DNA fragments in mixture
     
12. Random-primed reverse transcriptase-in vitro transcription method for RNA amplification
     
13. Method of target enrichment and amplification
     
14. Method for reducing artifacts in nucleic acid amplification
     
15. Random truncation and amplification of nucleic acid
     
16. Methods for DNA amplification and sequencing
     
17. Universal RT-coupled PCR method for the specific amplification of mRNA
     
18. Method to amplify variable sequences without imposing primer sequences
     
19. Complexity management of genomic DNA by locus specific amplification
     
20. Serial coupling of restriction cleavage and extension for nucleic acid amplification
     
21. Methods and compositions for amplification of RNA sequences
     
22. Shot-gun sequencing and amplification without cloning
     
23. Generation of single-strand circular DNA from linear self-annealing segments
     
24. Thermostable enzyme promoting the fidelity of thermostable DNA polymerases-for improvement of nucleic acid synthesis and amplification in vitro
     
25. Isothermal strand displacement nucleic acid amplification
     
26. Method for enrichment of natural antisense messenger RNA
     
27. Normalizing and amplifying RNA
     
28. Amplification process
     
29. Methods and compositions for amplification of RNA sequences using RNA-DNA composite primers
     
30. Method for linear mRNA amplification
     
31. Cycling DNA/RNA amplification electrochemiluminescent probe assay
     
32. Single-phase amplification of nucleic acids
     
33. Direct multiplex characterization of genomic DNA
     
34. Method for amplifying sequences from unknown DNA
     
35. Methods of small sample amplification

Genomics Research, Artificial Chromosomes

1. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes

Genomics Research, Cloning/Synthesizing/Purification

1. Use of RNA trans-splicing for antibody gene transfer and antibody polypeptide production
    
2. DNA joining method
    
3. Terminating substrates for DNA polymerases
    
4. Sir2 products and activities
    
5. Method for cloning variable domain sequences of immunological gene repertoire
    
6. Ribocloning: recombinant DNA construction using primers with ribo bases
    
7. Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
    
8. Recombination assembly of large DNA fragments
    
9. Method for producing a synthetic gene or other DNA sequence
    
10. Cloning and/or sequencing vector
     
11. Circular DNA vectors for synthesis of RNA and DNA
     
12. Method for cloning animals with targetted genetic alterations by transfer of long-term cultured male or female somatic cell nuclei, comprising artificially-induced genetic alterations, to enucleated recipient cells
     
13. Topoisomerase-based reagents and methods for molecular cloning
     
14. Methods of DNA purification and purified DNA
     
15. Method for synthesizing cDNA
     
16. Effective nuclear reprogramming in mammals using CDK2 inhibitors
     
17. Expression system for cloning toxic genes
     
18. Cloning and expression of HTLV-III DNA
     
19. Methods for insertion of nucleic acids into circular vectors
     
20. Vectors for improving cloning and expression in low copy number plasmids
     
21. Artificial chromosome
     
22. Rapid growing microorganisms for biotechnology applications

Genomics Research, Directed Evolution

1. Methods for in vivo diversification of single genes
    
2. In vitro evolution of nucleic acids and encoded polypeptide
    
3. Method for in vitro molecular evolution of protein function
    
4. Saturation mutageneis in directed evolution

Genomics Research, Gene Analysis/Identification/Isolation/Storage/Microarray

1. Characterisation of gene function using double stranded RNA inhibition
    
2. Random array DNA analysis by hybridization
    
3. System for monitoring the location of transgenes
    
4. Methods for haplotyping genomic DNA
    
5. Rapid analysis of variations in a genome
    
6. Assay for identifying compounds which affect stability of mRNA
    
7. Carrier of a diamond fine particle for immobilizing virus
    
8. Methods for genotyping hepatitis C virus
    
9. Genetic analysis and authentication
    
10. Method for the isolation of intact mitochondria from cells
     
11. Method for the detection of cytosine methylations in immobilized DNA samples
     
12. Methods for genotyping polymorphisms in humans
     
13. Gene chip technology for determining memory genes
     
14. Massive parallel method for decoding DNA and RNA
     
15. Polymorphisms in human mitochondrial DNA
     
16. Computer algorithm for automatic allele determination from fluorometer genotyping device
     
17. Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
     
18. T1R taste receptors and genes encoding same
     
19. Identification and mapping of single nucleotide polymorphisms in the human genome
     
20. Rapid analysis of variations in a genome
     
21. Compositions and methods for genetic analysis
     
22. Least-square deconvolution (LSD): a method to resolve DNA mixtures
     
23. Microarrays to screen regulatory genes
     
24. RNA detection assays
     
25. Methyltransferase gene and enzyme
     
26. Methods for separating and/or identifying DNA molecules
     
27. Method for isolating DNA from biological materials
     
28. Method for extracting DNA from organisms
     
29. Methods for identifying chromosomal aneuploidy
     
30. Rapid analysis of variations in a genome
     
31. Method of identifying cytosine methylation patterns in genomic DNA samples
     
32. Method for isolating DNA
     
33. Quantitative methylation detection in DNA samples
     
34. Design of artificial genes for use as controls in gene expression analysis systems
     
35. Method for accelerated genome walking and DNA fingerprinting
     
36. Process for labeling a ribonucleic acid
     
37. Frozen tissue microarray technology for analysis RNA, DNA, and proteins
     
38. Kit for determining DNA double-stranded breaks with anti-γ-H2A antibodies
     
39. Methods for detecting polymorphisms in nucleic acids
     
40. Method for isolating and recovering target DNA or RNA molecules having a desired nucleotide sequence
     
41. Complexity management of genomic DNA
     
42. Strand-specific polynucleotide nickases
     
43. Characterization of novel gene cbl-SL
     
44. Quantitative assay of host cell DNA in a sample
     
45. Methods of enhancing functional performance of nucleic acid arrays
     
46. Identification of sel-12 and uses thereof
     
47. Gene isolation method
     
48. Human secretory type phospholipase a2
     
49. Isolated mammalian membrane protein genes; related reagents
     
50. DNA encoding human apoB48R: a monocyte-macrophage apolipoprotein B48 receptor gene and protein
     
51. Gene transcription and ionizing radiation: methods and compositions
     
52. Methods and reagents for facilitating transcription
     
53. Dry solid medium for storage and analysis of genetic material

Genomics Research, Gene Expression

1. Gene expression and pain
    
2. Gene expression profiling of EGFR positive cancer
    
3. Aspergillus niger promoter for expressing genes in host cells
    
4. Multimodality imaging of reporter gene expression using a novel fusion vector in living cells and animals
    
5. Gene expression and pain
    
6. Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
    
7. Constitutive gene expression in conjunction with ionizing radiation
    
8. Gene expression markers for predicting response to chemotherapy
    
9. Method of classifying gene expression strength in lung cancer tissues
    
10. Means and methods for regulating gene expression
     
11. Methods for evaluating drug-resistance gene expression in the cancer patient
     
12. Gene and protein expression profiles associated with the therapeutic efficacy of irinotecan
     
13. Use of gene expression profiling to predict survival in cancer patient
     
14. Method for expression of small antiviral RNA molecules within a cell
     
15. Inhibition of gene expression using RNA interfering agents
     
16. Methods for monitoring multiple gene expression
     
17. Method for generating engineered cells by homologously recombining segments having increased degeneracy
     
18. Method and system for the multidimensional morphological reconstruction of genome expression activity
     
19. Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy
     
20. Regulation of gene expression using chromatin remodelling factors
     
21. Gene switch systems employing regulators with decreased dimerization
     
22. Multiplex spatial profiling of gene expression
     
23. Recombinant double-stranded RNA phage, and use of the same
     
24. Systems for expressing toxic proteins, vectors and method of producing toxic proteins
     
25. Multimodality imaging of reporter gene expression using a novel fusion vector in living cells and animals
     
26. Regulation of genes via application of specific and selective electrical and electromagnetic signals
     
27. RNA interference using a universal target
     
28. DNA virus microRNA
     
29. Lactose repressor proteins with increased operator DNA binding affinity
     
30. Artificial bidirectional promoter for activation of gene expression
     
31. Methods for monitoring multiple gene expression
     
32. Simultaneous modulation of multiple genes
     
33. Increased and sustained in vivo gene expression using a nucleic acid, histone and amphipathic compound composition
     
34. Compositions and methods for non-targeted activation of endogenous genes
     
35. Method for gene expression
     
36. Constructs for gene expression analysis
     
37. Human genes and gene expression products V
     
38. Binding proteins for recognition of DNA
     
39. Design principle for the construction of expression constructs for gene therapy
     
40. Retroviral vectors with foreign-sequence insertion between retroviral primer binding site and retroviral splice donor
     
41. Inducible expression vectors and methods of use thereof
     
42. Regulation of gene expression through manipulation of mRNA splicing and its uses
     
43. Compositions and methods for regulating RNA stability using polypyrimidine tract proteins
     
44. Methods for monitoring multiple gene expression
     
45. Method for the affinity isolation of newly synthesized RNA
     
46. Gene transfer in chicken bursal stem cells
     
47. Design of artificial genes for use as controls in gene expression analysis systems
     
48. Method of down-regulating gene expression
     
49. Modified DNA molecule, recombinant containing the same, and uses thereof
     
50. Modulation of endogenous gene expression in cells
     
51. Modulation of gene expression using localization domains
     
52. Methods for monitoring multiple gene expression
     
53. Method of screening for a biological response using linear and circular expression elements
     
54. Nucleic acid sequence for potentiating the expression of useful gene and method therefor
     
55. Cloning and expression of HTLV-III DNA
     
56. Delivery of therapeutic gene products by intestinal cell expression
     
57. Vectors for improving cloning and expression in low copy number plasmids
     
58. Expression of biologically active polypeptide in duckweed
     
59. Methods for regulating gene expression
     
60. Reagents and methods for identifying and modulating expression of genes regulated by retinoids
     
61. Methods to enhance and confine expression of genes
     
62. DNA molecules encoding hormone-dependent forms of the adeno-associated virus rep proteins
     
63. Regulation of gene expression by protein methylation
     
64. Methods for regulating gene expression using light
     
65. cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
     
66. Methods for analysis of gene expression
     
67. Method for separating and characterizing functions potentially present in a biological sample containing nucleic acids

Genomics Research, Gene Modification/Repair/Mutagenesis

1. Heat-resistant DNA ligase with high reactivity
    
2. Methods of cleaving DNA with rationally-designed meganucleases
    
3. Kit for measuring in vivo mutation frequency at an endogenous gene locus
    
4. Method of assessing DNA mutability
    
5. Targeted gene modification by parvoviral vectors
    
6. Hybrid recombinases for genome manipulation
    
7. Gene encoding a DNA repair enzyme and methods of use thereof
    
8. Artificial riboswitch for controlling pre-mRNA splicing
    
9. Allelic series of genomic modifications in cells
    
10. Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (MVA)
     
11. Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure
     
12. Random drift mutagenesis
     
13. Reducing cellular dysfunction caused by mitochondrial gene mutations
     
14. Method for detection of alterations in the DNA mismatch repair pathway
     
15. Methods and compositions for genomic modification
     
16. Gene repair involving in vivo excision of targeting DNA
     
17. Method for detection of alterations in the DNA mismatch repair pathway
     
18. Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
     
19. Method for massive directed mutagenesis
     
20. Circular site-directed mutagenesis
     
21. Broad specificity DNA damage endonuclease
     
22. Selection marker gene free recombinant strains
     
23. DNA repair enzymes, nucleic acids encoding DNA repair enzymes and methods of using them
     
24. Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
     
25. Fast method of transforming competent cells
     
26. Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
     
27. Method for generating genetically altered antigens
     
28. Transfer method for specific cellular localization of nucleic acids

Genomics Research, Gene Sequencing/Encoding

1. Massive parallel method for decoding DNA and RNA
    
2. DNA polymerase fusions and uses thereof
    
3. Gene encoding vitamin b.sub.6 phosphate phosphatase and use thereof
    
4. Method for sequencing nucleic acid sequences without chain termination
    
5. Stabilizing a nucleic acid for nucleic acid sequencing
    
6. Methods for DNA amplification and sequencing
    
7. Genes encoding for genetic stability, gene expression and folding proteins
    
8. Genetic suppression and replacement
    
9. DNA encoding novel estrogen receptor
    
10. Shot-gun sequencing and amplification without cloning
     
11. Method for detecting DNA polymorphism applying triple strand DNA formation technique
     
12. Polynucleotide sequencing
     
13. Methods of enhancing functional performance of nucleic acid arrays
     
14. Method for alignment of DNA sequences with enhanced accuracy and read length
     
15. Nuclease inhibitor cocktail
     
16. Thermostable DNA polymerase
     
17. Methods and reagents for preservation of DNA in bodily fluids
     
18. Removal of dye-labeled dideoxy terminators from DNA sequencing reactions

Genomics Research, Gene Silencing/Inhibition

1. Gene silencing
    
2. Apparatus and system having dry gene silencing pools
    
3. Methods and compositions for controlling efficacy of RNA silencing
    
4. Compositions for DNA mediated gene silencing
    
5. Genetic inhibition by double-stranded RNA
    
6. Modified polynucleotides for reducing off-target effects in RNA interference
    
7. siRNA targeting myeloid cell leukemia sequence 1
    
8. Compositions for DNA mediated gene silencing
    
9. Methods and compositions for DNA mediated gene silencing
    
10. RNA interference pathway genes as tools for targeted genetic interference
     
11. R2D2: an enzyme of RNA silencing
     
12. Muting gene activity using a transgenic nucleic acid
     
13. Gene silencing

Genomics Research, Genetic Detection/Screening System

1. Non-invasive detection of fetal genetic traits
    
2. Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
    
3. Differential enzymatic fragmentation by whole genome amplification
    
4. Screening method for gene variation
    
5. Chemo-centric selection of disease-related genetic profiles
    
6. Methods for detecting and localizing DNA mutations by microarray
    
7. Methods for genetic analysis
    
8. Binding proteins for recognition of DNA
    
9. Compositions and methods for repetitive use of genomic DNA
    
10. Cycling DNA/RNA amplification electrochemiluminescent probe assay
     
11. Complexity management of genomic DNA
     
12. Genetic screening methods
     
13. Direct multiplex characterization of genomic DNA
     
14. Adjustable sensitivity, genetic molecular interaction systems, including protein-protein interaction systems for detection and analysis

Genomics Research, Molecular Farming

1. Method for producing DNA
    
2. Method for stable chromosomal multi-copy integration of genes
    
3. Phage-dependent superproduction of biologically active protein and peptides
    
4. Molecular farming

Genomics Research, Synthetic Gene

1. Synthetic genes for enhanced expression

Genomics Research, Transcriptional Regulator/Rate

1. Potent combinations of mRNA transport elements
    
2. Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
    
3. Cyclic reverse transcription method
    
4. DNA sequences comprising gene transcription regulatory qualities and methods for detecting and using such DNA sequences
    
5. Recombinant reverse transcriptases
    
6. Position dependent recognition of GNN nucleotide triplets by zinc fingers
    
7. Genome wide location and function of DNA binding proteins
    
8. Multiple gene transcription activity assay system
    
9. Tet repressor-based transcriptional regulatory proteins
    
10. Method of reverse transcription
     
11. Methods of identifying synthetic transcriptional and translational regulatory elements, and compositions relating to same
     
12. Splice choice antagonists as therapeutic agents
     
13. Artificial bidirectional promoter for activation of gene expression
     
14. Ligand activated transcriptional regulator proteins
     
15. Transcriptional regulatory factor
     
16. Method of regulating transcription in a cell
     
17. Modulating transcription of genes in vascular cells
     
18. Process for producing peptides by using in vitro transcription/translation system
     
19. Method for the identification of gene transcripts with improved efficiency in the treatment of errors
     
20. Sequences characteristic of hypoxia-regulated gene transcription
     
21. DNA sequences for regulating transcription
     
22. Method for improving the stability of linear DNA in cell-free in vitro transcription/translation systems
     
23. Regulated transcription of targeted genes and other biological events
     
24. Transcription factors related to TFIIA
     
25. Transcriptional activators
     
26. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
     
27. Ribozyme-encoding DNA and a composition containing an oligonucleotide substrate and a method for measuring transcription rates
     
28. Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization
     
29. Transcriptional regulation of the human .beta.3-adrenergic receptor gene
     
30. Transcriptional regulator

Genomics Research, Transducing Phages

1. Transducing phages

Genomics Research, Vectors

1. Methods for insertion of nucleic acids into circular vectors
    
2. Paramyxovirus vectors used for transfer of foreign genes
    
3. Gene targeting using replicating DNA molecules
    
4. Viral recombinant vectors for expression in muscle cells
    
5. Recombinant adenovirus
    
6. Use of recombinant gene delivery vectors for treating or preventing lysosomal storage disorders
    
7. Vectors that repress heterologous promoter activity
    
8. Mutant herpes simplex viruses and uses thereof
    
9. Adenoviral vector with a deletion in the E1A coding region expressing a hetorologous protein
    
10. Packaging systems for human recombinant adenovirus to be used in gene therapy
     
11. Controlling immune response to specific antigens
     
12. Vectors for the diagnosis and treatment of solid tumors including melanoma
     
13. Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
     
14. Poliovirus replicons encoding therapeutic agents and uses thereof
     
15. Triple hybrid amplicon vector systems to generate retroviral packaging lines
     
16. Herpes simplex virus amplicon vector targeting system and method of using same
     
17. Methods for enhanced virus-mediated DNA transfer using molecules with virus-and cell-binding domains
     
18. Targeting adenovirus with use of constrained peptide motifs
     
19. Herpes virus vectors for dendritic cells
     
20. Tissue-vectors specific replication and gene expression
     
21. Targeted vectors
     
22. Adenoviral-vector-mediated gene transfer into medullary motor neurons
     
23. Temperature-sensitive regulation of viral vector production
     
24. HSV viral vector
     
25. Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
     
26. Adenoviral vectors with tandem fiber proteins
     
27. Methods of administering adenoviral vectors
     
28. Metabolically activated recombinant viral vectors and methods for the preparation and use
     
29. System for the in vivo delivery and expression of heterologous genes in the bone marrow
     
30. Hybrid vectors for gene therapy
     
31. Chimeric viral packaging signal without gag gene sequences
     
32. Producer cell that generates adenoviral vectors encoding a cytokine and a conditionally lethal gene
     
33. Insertional mutations in mycobacteria
     
34. Permanent amniocytic cell line, its production and use for the production of gene transfer vectors
     
35. Complex of biotinylated viral vector and ligand for targeted gene delivery
     
36. Retroviral gene transfer vectors
     
37. Retroviral gene therapy vectors and therapeutic methods based thereon
     
38. Adenoviral helper vectors
     
39. Adenoviral vectors encoding a cytokine and a conditionally lethal gene
     
40. Invasive bacterial vectors for expressing alphavirus replicons
     
41. Preparation of recombinant adenovirus carrying a rep gene of adeno-associated virus
     
42. Lentivirus-based gene transfer vectors
     
43. Viral vector complexes having adapters of predefined valence
     
44. Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
     
45. Methods of administering adenoviral vectors
     
46. Recombinant AAV packaging systems
     
47. Recombinant adenoviral vectors comprising a splicing sequence 
    
    
48. Use of herpes vectors for tumor therapy
    
    
49. Cloning vector
     
    
50. Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof

Growth Factors

1. Growth factor homolog ZVEGF4
    
2. Platelet-derived growth factor analogues

Handling/Storage, Biological Materials

1. Concentration and lysis of adenovirus-infected cells in a single unit operation
    
2. Methods of forming a humidity barrier for the ambient temperature preservation of sensitive biologicals

Handling/Storage, Microbiological Materials

1. Viable dried bacteria produced by drying in the presence of trehalose and divalent cation