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Patent Classification

Gene, Therapy/Delivery/Identification

  1. Targeted cross-linked nanoparticles and their use in vivo gene delivery
     
  2. Ocular gene therapy using avalanche-mediated transfection
     
  3. Polymeric carrier for delivery of small interfering RNA
     
  4. In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors
     
  5. Delivery of DNA or RNA via gap junctions from host cells to target cells and a cell-based delivery system for antisense or siRNA
     
  6. Tetracycline-regulated adeno-associated viral (AAV) vectors for gene delivery to the nervous system
     
  7. Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy
     
  8. Virus envelope vector for gene transfer
     
  9. Hepatocyte growth factor gene therapy for parkinson's disease
     
  10. Small interference RNA gene therapy
     
  11. Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyl transferase
     
  12. Methods of controlling cell differentiation and growth using a fusion protein and a drug
     
  13. Methods of gene transfer to astrocytes with mokola virus pseudotyped lentivirus vectors
     
  14. Enhancement of the immune response for vaccine and gene therapy applications
     
  15. Mammalian tumor susceptibility gene products and their uses
     
  16. Methods for delivering DNA to muscle cells using recombinant adeno-associated virus virions
     
  17. Compositions and methods for systemic nucleic acid sequence delivery
     
  18. Settings for recombinant adenoviral-based vaccines
     
  19. Methods and compositions for heat activated gene therapy using cytolethal distending toxin
     
  20. Methods of treating lysosomal storage related diseases by gene therapy
     
  21. Antibodies to M-CSF
     
  22. Hirulog-like peptide and gene therapy
     
  23. Gene switch systems employing regulators with decreased dimerization
     
  24. Nucleic acid injected into hepatic vein lumen
     
  25. Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the CNS
     
  26. Photochemical internalization for virus-mediated molecule delivery into the cyosol
     
  27. Gene therapy for tumors using minus-strand RNA viral vectors encoding immunostimulatory cytokines
     
  28. Genetic screen for bioactive peptides
     
  29. Gene regulation therapy involving ferritin
     
  30. Use of targeted cross-linked nanoparticles for in vivo gene delivery
     
  31. Method for introducing a biological molecule using a viral envelope and heparin and system therefore
     
  32. Antibody fragment-targeted immunoliposomes for systemic gene delivery
     
  33. Cancer cell targeting gene delivery method
     
  34. Compounds promoting delivery of genes
     
  35. Viral vectors for gene therapy
     
  36. Tetracycline-regulated adeno-associated viral (AAV) vectors for gene delivery to the nervous system
     
  37. AAV vectors for gene delivery to the lung
     
  38. Sustained DNA delivery from structural matrices
     
  39. Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
     
  40. In vivo production and delivery of erythropoietin or insulinotropin for gene therapy
     
  41. Adenovirus serotype 30 (Ad30)
     
  42. Method of delivering genes to the central nervous system of a mammal
     
  43. Vectors with modified protease-dependent tropism
     
  44. Use of nanoparticles for the DNA administration to a target organ
     
  45. Methods for cardiac gene transfer
     
  46. Systemic gene delivery vehicles for the treatment of tumors
     
  47. Method of expressing foreign gene in kidney
     
  48. GLP-1 gene delivery for the treatment of type 2 diabetes
     
  49. Gene therapy agent for Haemophilia B and its preparation method
     
  50. Tumor-specific vector for gene therapy
     
  51. Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells
     
  52. Methods and products for delivering biological molecules to cells using multicomponent nanostructures
     
  53. Gene therapy using TGF-.beta.
     
  54. Stable lipid-comprising drug delivery complexes and methods for their production
     
  55. Photocleavable DNA transfer agent
     
  56. Ligand activated transcriptional regulator proteins
     
  57. Growth factor therapy mobilization of stem cells into the peripheral blood
     
  58. Tumor radiosensitization using gene therapy
     
  59. Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
     
  60. Mixed-cell gene therapy
     
  61. Method of acquiring immunological tolerance
     
  62. Self-rearranging DNA vectors
     
  63. Methods for treating or preventing angiogenesis-dependent symptoms
     
  64. Gene delivery compositions and methods
     
  65. Gene delivery vehicle expressing the aptosis-inducing proteins VP2 and/or apoptin
     
  66. Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
     
  67. Herpes virus strains for gene therapy
     
  68. Gene therapy by small fragment homologous replacement
     
  69. Devices and processes for distribution of genetic material to mammalian limb
     
  70. Bovine immunodeficiency virus (BIV) based vectors
     
  71. Myeloid precursor cell useful for gene therapy and for modulation of immune responses
     
  72. Compositions for gene therapy of rheumatoid arthritis including a gene encoding an anti-angiogenic protein or parts thereof
     
  73. Virus vectors and methods of making and administering the same
     
  74. Nucleic acid formulations for gene delivery and methods of use
     
  75. Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms
     
  76. Hyaluronic acid mediated adenoviral transduction
     
  77. Nucleic acid injected into hapatic vein lumen and delivered to primate liver
     
  78. Human monoclonal antibodies to interleukin-5
     
  79. Compositions for receptor/liposome mediated transfection and methods of using same
     
  80. Vesicular monoamine transporter gene therapy in parkinson's disease
     
  81. Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies
     
  82. Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
     
  83. Methods for enhanced retroviral-mediated gene transfer
     
  84. Retroviral vectors including modified envelope escort proteins
     
  85. Design principle for the construction of expression constructs for gene therapy
     
  86. Defective adenoviruses and corresponding complementation lines
     
  87. Use of soluble costimulatory factor for tumor immuno-gene therapy
     
  88. Inducible expression vectors and methods of use thereof
     
  89. Packaging systems for human recombinant adenovirus to be used in gene therapy
     
  90. Stress-responsive induction of a therapeutic agent and methods of use
     
  91. Mutant NURR1 gene in Parkinson's disease
     
  92. Hematopoietic stem cell proliferating agents
     
  93. Reversible masking of liposomal complexes for targeted delivery
     
  94. Recombinant adenoviruses for gene therapy in cancers
     
  95. Isolated mammalian membrane protein genes; related reagents
     
  96. Use of marrow-derived glial progenitor cells as gene delivery vehicles into the central nervous system
     
  97. Particles for gene therapy
     
  98. Recombinant double-stranded RNA phage, and use of the same
     
  99. Intravascular delivery of nucleic acid
     
  100. Mixed-cell gene therapy
     
  101. Compositions comprising tissue specific adenoviral vectors
     
  102. Vector for reversible gene integration
     
  103. Methods of preparing bone marrow stromal cells for use in gene therapy
     
  104. Recombinant adenoviral vector and methods of use
     
  105. Gene therapy for cardiomyopathy
     
  106. Enhanced expression of transgenes
     
  107. Gene therapy by administration of genetically engineered CD34+ cells obtained from cord blood
     
  108. Vectors derived from South African Arbovirus No. 86
     
  109. Gene therapy by cell specific targeting
     
  110. Vector for the expression of two foreign genes
     
  111. Inhibition of vascular smooth muscle cell proliferation
     
  112. Circular DNA molecule with conditional origin of replication, method for preparing the same and use thereof in gene therapy
     
  113. KVLQT1—a long QT syndrome gene
     
  114. Methods for producing high titre vectors and compositions used in such methods
     
  115. Adiponectin gene therapy
     
  116. Methods and reagents for the detection of antibodies to adenovirus
     
  117. AAV2 vectors and methods
     
  118. Adenoviral vectors encoding an antibody fused to a CD4 extracellular domain
     
  119. Packaging cells comprising codon-optimized gagpol sequences and lacking lentiviral accessory proteins
     
  120. Compositions and methods for helper-free production of recombinant adeno-associated viruses
     
  121. Vectors and methods for gene transfer
     
  122. Replicating adenovirus vectors
     
  123. Antitumour vector constructs and methods
     
  124. Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
     
  125. Gene therapy for cerebrovascular disorders
     
  126. Tumour-specific vector for gene therapy
     
  127. Modulation of endogenous gene expression in cells
     
  128. Relationship of ABC transport proteins with hematopoietic stem cells and methods of use thereof
     
  129. Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
     
  130. Neurogenesis inducing genes
     
  131. Methods and compositions for enhancing the delivery of a nucleic acid to a cell
     
  132. Virus envelope vector for gene transfer
     
  133. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
     
  134. Gene delivery vectors with cell type specificity for mesenchymal stem cells
     
  135. Retroviral vectors, methods for their preparation and their use for gene transfer into CD4-positive cells
     
  136. Gene delivery system and methods of use
     
  137. Method of inducing tumor cell apoptosis using trail/Apo-2 ligand gene transfer
     
  138. Polynucleotide complex delivery
     
  139. Particle delivery techniques
     
  140. Controlled surface-associated delivery of genes and oligonucleotides
     
  141. Methods and compositions for the treatment of defects in lipoprotein metabolism
     
  142. Gene therapy vehicle comprising dermal sheath tissue
     
  143. Protection from ionizing irradiation or chemotherapeutic drug damage by in vivo gene therapy
     
  144. Peptides derived from STEAP1
     
  145. Selective precipitation of viruses
     
  146. Antitumoral composition based on immunogenic polypeptide with modified cell location
     
  147. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and virues
     
  148. Formation of polyampholytes in the presence of a polyion
     
  149. Packaging systems for human recombinant adenovirus to be used in gene therapy
     
  150. Methods and compositions for efficient gene transfer using transcomplementary vectors
     
  151. Monocyte-specific particulate delivery vehicle
     
  152. In vitro process for selecting phage resistant to blood inactivation
     
  153. Gene Therapy for proliferative vitreoretinopathy
     
  154. Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
     
  155. Bovine immunodeficiency virus (BIV) based vectors
     
  156. Methods of treating various cancers using melanoma differentiation associated protein
     
  157. Methods and compositions for increasing the infectivity of gene transfer vectors
     
  158. Gene delivery compositions and methods
     
  159. Tumor targeted vector
     
  160. Reverse gene therapy
     
  161. Combination therapy using nucleic acids and radio therapy
     
  162. Immunomodulation by genetic modification of dendritic cells and B cells
     
  163. Site specific recombinase based method for producing adenoviral vectors
     
  164. Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles
     
  165. In vitro construction of SV40 viruses and pseudoviruses
     
  166. Delivery of therapeutic gene products by intestinal cell expression
     
  167. Method of observing vasculogenesis in vitro using cultured allantois
     
  168. Infectivity-enhanced conditionally-replicative adenovirus and uses thereof
     
  169. Replication incompetent herpes viruses for use in gene therapy
     
  170. Vectors and methods for immunization or therapeutic protocols
     
  171. Cardiac-cell specific enhancer elements and uses thereof
     
  172. Retroviral delivery system
     
  173. Methods for encapsulating plasmids in lipid bilayers
     
  174. Synthetic transfection vectors
     
  175. Method for the identification of a receptor
     
  176. Methods for the administration of adenovirus p53
     
  177. Methods for compositions for in vivo gene delivery
     
  178. Gene delivery vectors with cell type specificity for primary human chondrocytes
     
  179. High efficiency transfection based on low electric field strength, long pulse length
     
  180. Lentiviral-mediated growth factor gene therapy for neurodegenerative diseases
     
  181. Recombinant adenoviruses expressing interleukin-18 protein and gene therapy using them
     
  182. Gene therapy using TGF-.beta
     
  183. Retrovirus vectors derived from avian sarcoma leukosis viruses permitting transfer of genes into mammalian cells and therapeutic uses thereof
     
  184. Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
     
  185. Gene therapy method for reducing risk of atherosclerosis
     
  186. Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization
     
  187. Mammalian genes involved in viral infection and tumor suppression
     
  188. Encapsulated cells producing viral particles
     
  189. Folypolyglutamyl synthetase gene transfer to enhance antifolate
     
  190. Method for the quantitation of alphavirus replicon particles
     
  191. Herpes simplex virus expressing foreign genes and method for treating cancers therewith
     
  192. Method for targeted delivery of nucleic acids
     
  193. Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
     
  194. Recombinant adeno viruses comprising an inserted gene encoding apolipoprotein and their use in gene therapy for dyslipoproteinemias
     
  195. Vectors including foreign genes and negative selective markers
     
  196. Cancer gene therapy based on translational control of a suicide gene
     
  197. Adenovirus vectors for the transfer of foreign genes into cells of the central nervous system particularly in brain
     
  198. DNA molecules encoding hormone-dependent forms of the adeno-associated virus rep proteins
     
  199. Targeted liposome gene delivery
     
  200. Compositions and methods for elimination of unwanted cells
     
  201. Paramyxovirus vectors used for transfer of foreign genes
     
  202. Therapy for cellular accumulation in chronic inflammatory diseases
     
  203. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
     
  204. Method of making microencapsulated DNA for vaccination and gene therapy
     
  205. Viral recombinant vectors for expression in muscle cells
     
  206. Recombinant adenovirus
     
  207. SOX-9 gene and protein and use in the regeneration of bone or cartilage
     
  208. Methods for regulating gene expression using light
     
  209. Methods for encapsulating nucleic acids in lipid bilayers
     
  210. Combination immunogene therapy
     
  211. Use of recombinant gene delivery vectors for treating or preventing lysosomal storage disorders
     
  212. Vectors that repress heterologous promoter activity
     
  213. Gene-entrapped liposomes preparation and process for the preparation thereof
     
  214. Use of lithium (Li+) for the preparation of a composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy
     
  215. Mutant herpes simplex viruses and uses thereof
     
  216. Genes identified as required for proliferation in Escherichia coli
     
  217. Transfer method for specific cellular localization of nucleic acids
     
  218. Artificial chromosome
     
  219. Treatment of pancreatic adenocarcinoma by cytotoxic gene therapy
     
  220. Encapsulated cells containing an amplified expression vector as a drug delivery device
     
  221. Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
     
  222. Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the CNS
     
  223. Method of producing infectious reovirus
     
  224. Treatment of ocular neovascularization and related diseases
     
  225. Methods and compositions for therapies using genes encoding secreted proteins such as interferon-beta
     
  226. Packaging systems for human recombinant adenovirus to be used in gene therapy
     
  227. Controlling immune response to specific antigens
     
  228. Vectors for the diagnosis and treatment of solid tumors including melanoma
     
  229. Recognition of tumor-specific gene products in cancer
     
  230. Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
     
  231. Human gene relating to respiratory diseases and obesity
     
  232. Mini-E1A gene and gene products
     
  233. Triple hybrid amplicon vector systems to generate retroviral packaging lines
     
  234. Method for gene therapy using nucleic acid loaded polymeric microparticles
     
  235. Herpes simplex virus amplicon vector targeting system and method of using same
     
  236. Method of diagnosing ischemic stroke via UCP-2 detection
     
  237. Methods for enhanced virus-mediated DNA transfer using molecules with virus-and cell-binding domains
     
  238. Identification of the gene causing the mouse scurfy phenotype and its human ortholog
     
  239. Microencapsulated DNA for vaccination and gene therapy
     
  240. Pancreatic cancer genes
     
  241. Use of trans-activation and CIS-activation to increase the persistence of a transgene in an at least E4-deficient adenovirus
     
  242. Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes
     
  243. Glucocorticoid enhancement of gene expression
     
  244. Targeting adenovirus with use of constrained peptide motifs
     
  245. Somatic cell gene therapy
     
  246. Herpes virus vectors for dendritic cells
     
  247. Tissue-vectors specific replication and gene expression
     
  248. Targeted vectors
     
  249. Adenoviral-vector-mediated gene transfer into medullary motor neurons
     
  250. Gene therapy for obesity
     
  251. Single-chain insulin analog and a polynucleotide sequence encoding the analog
     
  252. Methods and compositions for in vivo gene therapy
     
  253. Temperature-sensitive regulation of viral vector production
     
  254. Materials and methods for intracellular delivery of biologically active molecules
     
  255. Method for nucleic acid transfection of cells
     
  256. Polymeric gene delivery system
     
  257. Methods of in vivo gene transfer using a sleeping beauty transposon system
     
  258. HSV viral vector
     
  259. Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
     
  260. Methods and compositions for treatment of diabetes and related conditions via gene therapy
     
  261. Trans-somatics with gene transfer into mammary epithelial cells
     
  262. Adenoviral vectors with tandem fiber proteins
     
  263. Modulating transcription of genes in vascular cells
     
  264. Methods of administering adenoviral vectors
     
  265. Mutant having uracil phosphoribosyl transferase activity
     
  266. Metabolically activated recombinant viral vectors and methods for the preparation and use
     
  267. Cell-based gene therapy
     
  268. Recombinant yellow fever virus and method of use thereof
     
  269. Agent for gene therapy of dilated cardiomyopathy
     
  270. Mutants of the Rb and p53 genes and uses thereof
     
  271. Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
     
  272. Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
     
  273. System for the in vivo delivery and expression of heterologous genes in the bone marrow
     
  274. Medical use of gene and vector encoding a multisubstrate deoxyribonucleoside kinase
     
  275. Lipoxygenase proteins and polynucleotides encoding the same
     
  276. Lymphoma-susceptible transgenic mice and methods for studying drug sensitivity of lymphomas
     
  277. Adenovirus-mediated gene therapy
     
  278. Hybrid vectors for gene therapy
     
  279. Chimeric viral packaging signal without gag gene sequences
     
  280. Genetic constructs for delaying or repressing the expression of a target gene
     
  281. Producer cell that generates adenoviral vectors encoding a cytokine and a conditionally lethal gene
     
  282. Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cell
     
  283. Method for gene transfer to the central nervous system
     
  284. Cell-based drug screens for regulators of gene expression
     
  285. NK-1 receptor antagonists for prevention of neurogenic inflammation in gene therapy
     
  286. Permanent amniocytic cell line, its production and use for the production of gene transfer vectors
     
  287. Microencapsulation and sustained release of oligonucleotides
     
  288. Complex of biotinylated viral vector and ligand for targeted gene delivery
     
  289. Method of stable integration of DNA into neurons
     
  290. Tumor radiosensitization using gene therapy
     
  291. Muscle reinnervation and motor axon sprouting by administering DNA sequences encoding NT-3 and CNTF
     
  292. Retroviral gene transfer vectors
     
  293. Retroviral gene therapy vectors and therapeutic methods based thereon
     
  294. Methods and reagents for facilitating transcription
     
  295. Therapeutic Gene
     
  296. Adenoviral helper vectors
     
  297. Vaccina virus comprising cytokine and/or tumor associated antigen genes
     
  298. CaESS1: a Candida albicans gene, methods for making and using, and targeting it and its expression products for antifungal applications
     
  299. Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby
     
  300. Compositions and methods for wound healing
     
  301. Protected one-vial formulation for nucleic acid molecules, methods of making the same by in-line mixing, and related products and methods
     
  302. Methods for encapsulating plasmids in lipid bilayers
     
  303. In vivo production and delivery of insulinotropin for gene therapy
     
  304. Adenoviral vectors encoding a cytokine and a conditionally lethal gene
     
  305. Invasive bacterial vectors for expressing alphavirus replicons
     
  306. Gene therapy for the treatment of solid tumors using recombinant adeno-associated virus vectors
     
  307. Use of G-actin for improving transfection of a polynucleotide into a cell
     
  308. Method of suppressing tumor cell growth by administering a decorin gene or gene product
     
  309. Preparation of recombinant adenovirus carrying a rep gene of adeno-associated virus
     
  310. Gene construct and its use
     
  311. Lentivirus-based gene transfer vectors
     
  312. Enzyme combinations for destroying proliferative cells
     
  313. Formulated nucleic acid compositions and methods of administering the same for gene therapy
     
  314. Vesicular monoamine transporter gene therapy in Parkinson's disease
     
  315. Viral vector complexes having adapters of predefined valence
     
  316. Method of plasmid DNA production and purification
     
  317. Methods for preventing graft rejection in transplantation and for producing a universal gene therapy host cell using lymphocyte activation (LAG-3)
     
  318. Adeno-associated virus capsid immunologic determinants
     
  319. Complex of DNA and microparticle of defatted lipid-binding protein for gene therapy
     
  320. In vitro sorting method
     
  321. Retroviral packaging cassettes amplified in the cytoplasm by autocatalytic Togavirus vectors
     
  322. Method of intranasal gene transfer for protection against respiratory infection
     
  323. Gene treatment to enhance feed efficiency and growth rate of livestock
     
  324. Cell-based gene therapy for the pulmonary system
     
  325. Methods to inhibit or enhance the binding of viral DNA to genomic host DNA
     
  326. Development of viruses resistant to inactivation by the human complement system
     
  327. Polymeric gene delivery
     
  328. Gene-containing compositions
     
  329. Expression of cloned genes in the lung by aerosol and liposome-based delivery
     
  330. Transgene expression in polarized cells
     
  331. Materials and methods for gene therapy
     
  332. Production of chimeric antibodies with specificity to human tumor antigens
     
  333. Purging leukemia cells from hematopoietic stem cells
     
  334. Assays for promoter operability in central nervous system cells
     
  335. Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
     
  336. Pituitary-tumor-transforming-genes, and related products
     
  337. DNA molecules encoding single strand gap response proteins involved in activation of a DNA repair/cell cycle checkpoint pathway
     
  338. Design principle for construction of expression constructs for gene therapy
     
  339. Regulated expression of recombinant proteins using RNA viruses
     
  340. Methods of administering adenoviral vectors
     
  341. Delivery system for gene therapy to the brain
     
  342. Adenovirus-medicated gene transfer to cardiac and vascular smooth muscle
     
  343. Method of enhancing the effectiveness of DCK phosphorylated molecules
     
  344. Method for the augmentation of gene expression
     
  345. Zymogen activation system
     
  346. Virus-like particles useful as a vector for delivering nucleic acid
     
  347. Receptor-binding pocket mutants of influenza a virus hemagglutinin for use in targeted gene delivery
     
  348. Methods and reagents for inhibiting proliferation of smooth muscle cells
     
  349. Sensitizing cells to compounds using lipid-mediated gene and compound delivery

  350. Targeted gene delivery system

  351. In Utero treatment of CFTR-related deficiencies

  352. Recombinant adenoviral vectors comprising a splicing sequence 

  353. Gene transfer in chickens by introduction of DNA into muscle in ovo

  354. Uteroglobin gene therapy for epithelial cell cancer

  355. Cationic peptides, Cys-Trp-(Lys)n, for gene delivery

  356. Intravascular delivery of non-viral nucleic acid

  357. Gene delivery compositions and methods

  358. Proteins related to encapsulation and genes encoding the same

  359. Non-invasive gene targeting to the brain

  360. Transgene expression systems

  361. Use of a melanoma differentiation associated gene (mda-7) for inducing apoptosis of a tumor cell

  362. Methods for using the obese gene and its gene product to stimulate hematopoietic development

  363. Transcriptional inhibitor

  364. Gene therapy for pulmonary edema using adenovirus vectors encoding Na,K-ATPase

  365. Transposition assembly for gene transfer in eukaryotes

  366. Method for preparing a viral aerosol and its use in gene therapy treatment

  367. Method for detection and treatment of breast cancer 

  368. Radiation enhanced gene therapy for tumors expressing a gene for a viral pyrimidine kinase in the presence of a 5'-halogenated pyrimidine 

  369. Lipid vesicles containing adeno-associated virus rep protein for transgene integration and gene therapy 

  370. Integrative protein-DNA cochleate formulations and methods for transforming cells
     
  371. Episomal expression vector for human gene therapy
     
  372. Vectors and methods for immunization or therapeutic protocols
     
  373. Gene construct encoding a heterologous prodrug-activating enzyme and a cell targeting moiety
     
  374. Gene therapy in coronary angioplasty and bypass
     
  375. Methods for delivering DNA to muscle cells using recombinant adeno-associated virus virions to treat lysosomal storage disease
     
  376. Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
     
  377. Method for treatment in gene therapy and use of guanine derivative therefor
     
  378. Methods for use of Mpl ligands with primitive human stem cells
     
  379. Minimally invasive gene therapy delivery and method
     
  380. Coxsackie virus vectors for delivery of nucleic acids encoding antigenic or therapeutic products
     
  381. Method of enhancing the delivery of nucleic acids using silica nanoparticles
     
  382. Bovine adenovirus type 3 genome and vector systems derived therefrom
     
  383. Induction of angiogenesis in heart muscle by a DNA sequence encoding an angiogenic protein
     
  384. Delivery of nucleic acid materials
     
  385. Gene therapy for congestive heart failure
     
  386. Genetically engineered retroviral vector particles capable of infecting non-dividing cells
     
  387. Compositions and methods for nucleic acid delivery to the lung
     
  388. Adenovirus-medicated gene transfer to cardiac and vascular smooth muscle
     
  389. Defective packaging non-oncoviral vectors based on HIV
     
  390. Intracellular delivery vehicles
     
  391. Gene transfer method with the use of serum-free medium
     
  392. Method for enhancing myoblast migration and invasion in the context of gene therapy
     
  393. Method for generating dopaminergic cells derived from neural precursors
     
  394. Immunomodulation by genetic modification of dendritic cells and B cells
     
  395. Use of a non-mammalian DNA virus to express an exogenous gene in a mammalian cell
     
  396. Isolated mammalian membrane protein genes; related reagents
     
  397. Method of making microencapsulated DNA for vaccination and gene therapy
     
  398. Sonic nebulized nucleic acid/cationic liposome complexes and methods for pulmonary gene delivery
     
  399. Packaging systems for human recombinant adenovirus to be used in gene therapy
     
  400. Polymeric gene delivery system
     
  401. Combination product for enhanced gene delivery comprising a hyaluronidase
     
  402. Gene delivery by secretory gland expression
     
  403. Method for gene therapy using nucleic acid loaded polymeric microparticles
     
  404. Medicament comprising HGF gene
     
  405. Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
     
  406. Method for treating brain cancer with a conditionally lethal gene
     
  407. Gene therapy for regulating bladder smooth muscle tone
     
  408. Transgenomic viruses
     
  409. Method and devices for creating a trap for confining therapeutic drugs and/or genes in the myocardium
     
  410. Protection of the esophagus from chemotherapeutic or irradiation damage by gene therapy
     
  411. Gene therapy for solid tumors, papillomas and warts
     
  412. Polyester analogue of poly-L-lysine as a soluble, biodegradable gene delivery carrier
     
  413. Biodegradable mixed polymeric micelles for gene delivery
     
  414. Gene expression in mammalian cells
     
  415. Ocular gene therapy
     
  416. Somatic gene therapy to suppress secondary cataract formation following eye surgery
     
  417. Genetic induction of anti-viral immune response and genetic vaccine for filovirus
     
  418. Compositions and methods for delivery of genetic material
     
  419. Targeted introduction of DNA into primary or secondary cells and their use for gene therapy and protein production
     
  420. Gene therapies for enhancing cardiac function
     
  421. Gene transfer for studying and treating a connective tissue of a mammalian host
     
  422. Delivery of polypeptide-encoding plasmid DNA into the cytosol of macrophages by attenuated listeria suicide bacteria
     
  423. Cell-specific molecule and method for importing DNA into a nucleus
     
  424. Materials and methods for delivery and expression of heterologous DNA in vertebrate cells
     
  425. Oral delivery of adeno-associated viral vectors
     
  426. Preparation of lipid-nucleic acid particles using a solvent extraction and direct hydration method
     
  427. Gene therapies for enhancing cardiac function
     
  428. Liposome-mediated transfection of central nervous system cells
     
  429. Gene therapy for cystic fibrosis
     
  430. Methods and compositions for use in gene therapy for treatment of hemophilia
     
  431. Method for gene therapy involving suppression of an immune response
     
  432. Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy
     
  433. Receptor ligand-facilitated delivery of biologically active molecules
     
  434. DNA molecule encoding for cellular uptake of Mycobacterium tuberculosis and uses thereof
     
  435. Targeted delivery of genes encoding interferon
     
  436. Gene-containing compositions
     
  437. Tissue-specific enhancer active in prostate
     
  438. In vivo production and delivery of erythropoietin for gene therapy
     
  439. Microsphere encapsulation of gene transfer vectors
     
  440. Method for importing biologically active molecules into cells
     
  441. Formulated nucleic acid compositions and methods of administering the same for gene therapy
     
  442. Formulated nucleic acid compositions and methods of administering the same for gene therapy
     
  443. Cationic lipids for gene therapy
     
  444. Packaging systems for human recombinant adenovirus to be used in gene therapy (*Large document -- long loading time)
     
  445. Gene up-regulated in regenerating liver
     
  446. Device and method for encapsulated gene therapy
     
  447. Formulations for non-viral in vivo transfection in the lungs
     
  448. Surface expression of enzyme in gene directed prodrug therapy
     
  449. Solid microparticles for gene delivery
     
  450. Modified protein for gene transfer and process for producing the same

 

     
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