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 Pharm/Biotech Patents Available for Licensing (US Government)

The following patents are owned by the United States Government and
available for licensing.

January 23, 2012

•  Notice (A): Government-Owned Inventions; Availability for Licensing
  • Enhancement of Cancer Imaging and Treatment With Somatostatin Analogs
  • PARP Inhibitor/NO Donor Dual Prodrugs as Anticancer Agents
  • Small Molecule Drugs for Treatment of Ataxia Telangiectasia or DNA Damage
  • Transgenic Human Interleukin-21 Mouse Model
  • Method for Producing Significant Amounts of B19 Virus for Development of Killed or Attenuated Vaccines
  • HIV Therapeutics Utilizing Peptide Secreting Commensal Bacteria
•  Notice (B): Government-Owned Inventions; Availability for Licensing
  • Thioxothiazolidinone Derivatives--A Novel Class of Anti Cancer Agents
  • Monospecific and Bispecific Human Monoclonal Antibodies Targeting IGF-II
  • Genetic Interactions That Predict Attention Deficit Hyperactivity Disorder Outcome and Severity
  • Modulating Autophagy as a Treatment for Lysosomal Storage Diseases

December 8, 2011

•  Notice: Government-Owned Inventions; Licensing and Collaborative Research Opportunity: Chemotoxins for Targeted Treatment of Diseased Cells
  • Chemotoxins for Targeted Treatment of Diseased Cells
•  Notice: Government-Owned Inventions; Availability for Licensing
  • Novel NSAIDs for the Treatment of Human Diseases
  • Fibroblast Growth Factor Receptor 1 (Fgfr1) Conditional Knock Out Mouse
  • Biomarkers for Cancer-Related Fatigue and Their Use in the Management of Such Fatigue (CRF)
  • Characterizing Compartment Distributions From Diffusion Weighted Magnetic Resonance (MR) Data
  • One Step Fluorine-18 Peptide Labeling Strategy of Biological Substrates


November 25, 2011

•  Notice: Government-Owned Inventions; Availability for Licensing
  • Genetically Engineered Mouse Model for Use as an Alternative Screening Method for Evaluating P-glycoprotein (P-gp) Substrate Toxicity in
  • Avermectin-sensitive Dogs
  • Treatment of Tuberculosis--Adjuvant Therapies To Increase the Efficiency of Antibiotic Treatments
  • DPEP1 and TPX2 as Prognostic Biomarkers for Pancreatic Ductal Adenocarcinoma
  • AAV Mediated CTLA-4 Gene Transfer To Treat Sj[ouml]gren's Syndrome

November 22, 2011

•  Notice: Government-Owned Inventions; Availability for Licensing
  • Medical Device for Intraocular Injection of Therapeutics and Fluid Sampling
  • Bacteria/Biofilm Resistant Implantable Medical Device

October 27, 2011

•  Notice (A): Government-Owned Inventions; Availability for Licensing
  • Protease Deficient Bacillus anthracis With Improved Recombinant Protein Yield Capabilities
  • Parvovirus B19 Codon Optimized Structural Proteins for Vaccine and Diagnostic Applications
•  Notice (B): Government-Owned Inventions; Availability for Licensing
  • New Non-HLA-A2 Restricted Human T Cell Receptors (TCRs) That Could Be Used To Treat a Broader Cancer Patient Population Via TCR Adoptive Immunity
  • Antiandrogen Small Molecules for the Treatment of Prostate Cancer

October 12, 2011

•  Notice: Government-Owned Inventions; Availability for Licensing
  • Human Phospho-Serine134 Glucocorticoid Receptor Polyclonal Antibody: Useful for the Characterization of Glucocorticoid Signaling Processes, e.g., in Cancer and Inflammation
  • Infectious Hepatitis E Virus Genotype 3 Recombinants--Prospective Vaccine Candidates and Vector System
  • Diagnostic H5N1 Avian Influenza Virus Peptides

October 5, 2011

•  Notice (A): Government-Owned Inventions; Availability for Licensing
  • Platform Technology Using Ubiquitin To Improve the Delivery and Efficacy of Cytosolic Targeted Toxins
  • NOX5 Immunogenic Peptides and Monoclonal Antibodies for the Detection of Cancer and Inflammatory Responses
  • mGluR5 Tumor Mouse Model
  • Monoclonal Antibodies to FCRL5 (CD307e/IRTA2/FcRH5) as Therapeutics and Diagnostics for B-cell Cancers
  • Potent Inhibitory RNAs for Non-Surgical Treatment of Salivary Gland Cancers
•  Notice (B): Government-Owned Inventions; Availability for Licensing
  • Humanized Monoclonal Antibodies Efficient for Neutralization of Tick-Borne Encephalitis Virus (TBEV)
  • Rapid Molecular Assays for Specific Detection and Quantitation of Loa Loa Microfilaremia
  • Diagnostic Assays and Methods of Use for Detection of Filarial Infection
  • A System and Method for Detecting Untoward Events in Hospitals

September 26, 2011

•  Notice: Government-Owned Inventions; Availability for Licensing
  • A Novel Method To Predict Kidney Tumor Growth
  • Pharmaceutical Compounds for the Treatment of Spinal Muscular Atrophy and Other Uses
  • STAMP, A Novel Cofactor and Possible Steroid Sparing Agent, Modulates Steroid-induced Induction or Repression of Steroid Receptors
  • A Biomarker and Therapeutic Target for Ovarian Cancer

September 6, 2011

•  Notice (A): Government-Owned Inventions; Availability for Licensing
  • Fully Automated Bone Mineral Densitometry on Routine CT Scans
  • Filovirus Vaccines and Diagnostics Based on Glycoprotein-Fc Fusion Proteins
•  Notice (B): Government-Owned Inventions; Availability for Licensing
  • Vaccine To Prevent BK Polyomavirus-associated Kidney and Bladder Infections in Organ Transplant Recipients
  • Gas Permeable Flasks To Grow Tumor Infiltrating Lymphocytes (TIL) for More Effective Anti-Cancer Immunotherapy
  • A Novel Optomechanical Module that Enables a Conventional inverted Microscope To Provide Selective Plane Illumination Microscopy (iSPIM)
  • A Vaccine for Shigella sonnei for Both Children and Adults

August 18, 2011

•  Notice: Government-Owned Inventions; Availability for Licensing
  • Quantitative Measurement of Syndesmophytes in Ankylosing Spondylitis Using Computed Tomography (CT)
  • An Automated Method for Precise Measurement of Vertebral Body Height and Intervertebral Disk Height Using Computed Tomography
  • Monoclonal Antibodies Against Poliovirus
  • Methods of Treating Giardiasis Using FDA-Approved Compounds

August 11, 2011

•  Notice: Government-Owned Inventions; Availability for Licensing
  • Tumor Markers for Potentially Predicting Outcome of Anti-angiogenesis Therapy
  • TRRAP and GRIN2A Mutations for the Diagnosis and Treatment of Melanoma
  • Cells and Nanoparticles With Altered Protein Expression Patterns Useful for the Modulation of T Cell Activity for Immunotherapy

 

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