|
|

Title: Lipophilic carrier systems
United States Patent: 6,015,574
Inventors: Cannell; David W. (New York, NY); Mathur;
Hitren (Woodbridge, NJ); Nguyen; Nghi (Edison, NJ); Espino; Cynthia
(Princeton, NJ)
Assignee: L'Oreal (Paris, FR)
Appl. No.: 871524
Filed: June 9, 1997
Abstract
A composition containing an organic phospholipid capable of forming
bilayers in solution, a nonionic surfactant, and an amphoteric surfactant
in a combined amount sufficient to allow lipophilic ingredients to be
incorporated into an aqueous solution, and method for making such
compositions.
SUMMARY OF THE INVENTION
In order to achieve these and other advantages, the
present invention is drawn to a composition made up of at least one
organic phospholipid capable of forming bilayers in aqueous solution, at
least one nonionic surfactant, and at least one amphoteric surfactant. The
nonionic surfactant is present in an amount equal to or greater than the
amount of the organic phospholipid.
In another embodiment, the present invention relates to an aqueous
delivery system for lipophilic materials. The delivery (or
"carrier") system includes at least one organic phospholipid
capable of forming bilayers in aqueous solution, at least one nonionic
surfactant, at least one amphoteric surfactant, at least one lipophilic
ingredient, and an aqueous phase. The nonionic surfactant is present in an
amount by weight equal to or greater than the amount of the phospholipid.
The organic phospholipid, the nonionic surfactant, and the amphoteric
surfactant are present in a combined amount sufficient to allow the
lipophilic ingredient to be incorporated into the delivery system.
The present invention is also drawn to a process for the preparation of an
aqueous system comprising: (a) combining at least one organic phospholipid
capable of forming bilayers in aqueous solution, at least one nonionic
surfactant, and at least one amphoteric surfactant to form a mixture, (b)
heating the mixture obtained in step (a), (c) adding an aqueous solution
to form a diluted mixture, and (d) cooling the diluted mixture. Lipophilic
ingredients can be incorporated in step (a).
Claim 1 of 22 Claims
1. A composition comprising:
at least one organic phospholipid capable of forming bilayers in aqueous
solution;
at least one amphoteric surfactant; and
at least one nonionic surfactant present in an amount by weight equal to
or greater than the amount of said at least one phospholipid,
wherein said at least one phospholipid, said at least one amphoteric
surfactant, and said at least one nonionic surfactant are present in a
combined amount sufficient to allow lipophilic ingredients to be
incorporated into an aqueous solution containing said composition.
____________________________________________
If you want to learn more
about this patent, please go directly to the U.S.
Patent and Trademark Office Web site to access the full
patent.
|