Title:  Medicinal herbal composition for treating liver diseases and HIV

United States Patent:  6,455,078

Issued:  September 24, 2002

Inventors:  Wu; Tzu-Sheng (No. 3, Lane 14, Jian-Gung 1st Road, Hsinchu, 300, TW)

Appl. No.:  906791

Filed:  July 18, 2001

The present invention provides a herbal pharmaceutical composition for treating patients with liver diseases and/or HIV. The composition contains fifteen (15) ingredients, which are diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, milkvetch root, barbary wolfberry fruit, sanqi, red ginseng, figwort root, Chinese magnoliavine fruit, turmeric root-tuber, hawthorn fruit, and Chinese angelica. Among the fifteen (15) ingredients, diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit are the required herbs which contribute to the efficacy of the pharmaceutical composition.

BRIEF SUMMARY OF THE INVENTION

The novel medicinal composition of the present invention comprises herb extracts from diffuse hedyotis, giant knotweed rhizome, bistort rhizome, Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, milkvetch root, barbary wolfberry fruit, sanqi, red ginseng, figwort root, Chinese magnoliavine fruit, turmeric root-tuber, hawthorn fruit, and Chinese angelica. The composition is effective in treating patients with liver diseases, including, but not limited to viral hepatitis (e.g., HAV, HBV, and HCV, and HEV), alcoholic or fatty liver, liver cirrhosis and liver cancer. It is also effective for treating patients with HIV.

Among the herbs used in the composition, diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit are the necessary ingredients that provide for the efficacy of the composition. Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, tumeric root-tuber, hawthorn fruit, and sanqi are used mainly to improve or enhance the flavour, toning, and medicinal effects of, and to balance the excessive effects cause by diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit. In addition, barbary wolfberry fruit, red ginseng, figwort root, Chinese angelica and milkvetch root can be added to the composition to provide further nutrition to the liver during the recovery stage.

The weight ratio of diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit is preferred to be about 3:3:1:2. The weight ratio of diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Chinese magnoliavine fruit, asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, tumeric root-tuber, hawthorn fruit, and sanqi is preferred to be about 3:3:1:2:1:1:0.1:1:2:1. The weight ratio of diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Chinese magnoliavine fruit, asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, tumeric root-tuber, hawthorn fruit, sanqi, barbary wolfberry fruit, red ginseng, figwort root, Chinese angelica, and milkvetch root is preferred to be about 3:3:1:2:1:1: 0.1:1:2:1:3:1:2:1:3.

The present invention also provides a method for preparing the herbal pharmaceutical composition, which comprises the steps of: (1) grinding and mixing the entire plant of diffuse hedyotis, the dried rhizome of bistort rhizome, the dried rhizome of giant knotweed rhizome, and the dried ripe fruit of Chinese magnoliavine fruit to form a herbal mixture; (2) boiling the herbal mixture in water in two times (first by boiling the mixture in water for 2 hours, then, after the mixture has cooled down, boiling the mixture again for 1.5 hours); (3) filtering the boiled herbal mixture to separate the herbs from the herbal solution; (4) concentrating the herbal solution (preferrably concentrating from about 1.4 fold by volume to about 1 fold by volume); and (5) spray-drying and granulating the concentrated herbal solution into granules, which can be further encapsulated.

Claim 1 of 27 Claims

I claim:

1. An herbal pharmaceutical composition for treating patients with liver disease and/or HIV comprising a mixture of:

an entire plant of Herba Hedyotidis diffusae (diffuse hedyotis);

a dried rhizome of Rhizoma Bistortae (bistort rhizome);

a dried rhizome of Rhizoma Polygoni Cuspidati (giant knotweed rhizome); and

a dried ripe fruit of Fructus Schisandrae (Chinese magnoliavine fruit);

wherein said entire plant of diffuse hedyotis, said dried rhizome of bistort rhizome, said dried rhizome of giant knotweed rhizome, and said dried ripe fruit of Chinese magnoliavine fruit are in a weight ratio of about 3:3:1:2; and

wherein said mixture is extracted with water.
 

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