The present invention relates to a hair growth inhibitor and a depilation accelerator, each comprising a crude drug selected from Bupleuri Radix, Perillae Herba, Rhel Rhizoma and Akebiae Caulis, or an extract thereof. This inhibitor or accelerator makes it possible to inhibit the growth of body hair or promote depilation, respectively, thereby reducing the frequency of hair removal treatment. Moreover, it makes the hair body finer, thereby facilitating the removal of the hair from feet or arms.

Description of the Invention

TECHINICAL FIELD

The present invention relates to a hair growth inhibitor for retarding hair growth at arms or feet; and also a depilation accelerator.

BACKGROUND ART

The body hair of mammals serves to biologically protect important organs such as head, chest, arms and feet. In recent years, however, the body hair, particularly, that of arms and feet tends to be regarded undesirable from the aesthetic viewpoint. To meet such a tendency, a variety of body hair removing methods, such as mechanical removing method using a shaver, hair-tweezers or the like and, a method of rooting up the hair by using a depilatory and a method making use of the chemical action of a hair removing agent.

These hair removing methods however give a physical or chemical stimulus to the skin and are usually accompanied with a pain or discomfort. Although there is a little difference in durability among the methods, their effects do not last permanently, which requires further hair removal treatment after the passage of a predetermined time. There is accordingly a demand for reducing the frequency of the hair removal treatment.

An object of the present invention is therefore to provide a hair growth inhibitor and a depilation accelerator capable of suppressing hair growth and accelerating depilation, respectively, thereby reducing the frequency of the body hair removal treatment.

DISCLOSURE OF THE INVENTION

The present inventors have searched for highly safe natural substances. As a result, they have found that specific plants have excellent hair growth retarding action and depilation accelerating action.

In one aspect of the present invention, there is thus provided a hair growth inhibitor and a depilation accelerator, each comprising a crude drug selected from Bupleuri radix, Perillae herba, Rhei rhizoma and Akebiae caulis, or an extract thereof.

In another aspect of the present invention, there is also provided the use, for the preparation of a hair growth inhibitor or a depilation accelerator, of a crude drug selected from Bupleuri radix, Perillae herba, Rhei rhizoma and Akebiae caulis, or an extract thereof.

In a further aspect of the present invention, there is also provided a method for removing the body hair, which comprises applying, to the skin, a crude drug selected from Bupleuri radix, Perillae herba, Rhei rhizoma and Akebiae Caulis, or an extract thereof.

BEST MODES FOR CARRYING OUT THE INVENTION

The crude drugs to be contained in the hair growth inhibitor or depilation accelerator of the present invention are plant crude drugs. The "Bupleuri radix" is the root of Bupleurum falcatum L. belonging to the family of Umbelliferae or a variant thereof; "Perillae herba" is the greenery of Perilla frutescens Britton var. acuta Kudo or an allied species thereof belonging to the family of "Labiatae"; "Rhei rhizoma" is the tuber of Rheum palmatum L., Rheum tanguticum Maximowicz, Rheum officinale Baillon, or Rheum coreanum Nakai or a hybride therebetween belonging to the family of Polygonaceae; and "Akebiae caulis" is the volubile stem (usually, horizontally-cut one) of Akebia quinata Decaisne belonging to the family of Lardizabalaceae or a congener thereof. The above-described crude drugs have already been used as a drug or a raw material therefor, but they are utterly unknown to have hair growth suppressing action and depilation accelerating action.

The term "an extract thereof" as used herein means a solvent extract available by extracting the above-described crude drug at normal temperature or under heating or through an extracting device such as Soxhlet extractor, or its dilute solution, concentrate or dry powder. The extract may be a mixture of at least two of the above-described crude drugs.

Examples of the solvent used for extraction include water, alcohols such as methanol, ethanol, propanol and butanol, polyhydric alcohols such as polypropylene glycol and butylene glycol, ketones such as acetone and methyl ethyl ketone, esters such as methyl acetate and ethyl acetate, linear or cyclic ethers such as tetrahydrofuran and diethyl ether, halogenated hydrocarbons such as dichloromethane, chloroform and carbon tetrachloride, hydrocarbons such as hexane, cyclohexane and petroleum ether, aromatic hydrocarbons such as benzene and toluene, polyethers such as polyethylene glycol, pyridines, and supercritical carbon dioxide. They may be used either singly or in combination.

From the above-described extract, inactive impurities can be removed by a technique such as liquid-liquid partition. Use of such a purified extract is preferred in the present invention. If necessary, the extract may be used after deodorization or decoloring in a known manner.

The above-described crude drug or extract thereof can be used as is as the hair growth inhibitor or depilation accelerator of the present invention. It can also be used after dilution, or in the powder or paste form after concentration or lyophilization.

The crude drug or extract thereof thus prepared exhibits excellent hair growth suppressing action as shown later in Examples and has high safety so that a hair growth inhibitor available from the crude drug or extract thereof is usable as cosmetic, drug or quasi drug.

It is preferred to formulate the hair growth inhibitor or depilation accelerator of the present invention as a dermatologic preparation for external use, particularly, a hair-removing, depilatory or shaving cosmetic composition. Specific examples include hair removers in the form of a paste, cream or aerosol, depilatories in the form of a wax, gel or sheet, agents in the form of a lotion or cream used for treatment after hair removal or depilation, antiperspirant and deodorant cosmetic compositions such as deodorant lotion, deodorant powder, deodorant spray or deodorant stick, pre-shaving agents such as pre-shaving lotion, shaving agents such as shaving cream, and after-shaving agents such as after-shaving lotion.

In the hair growth inhibitor or depilation accelerator of the present invention, the particularly preferred content of the crude drug permitting the exhibition of hair growth suppressing effect or depilation accelerating effect is 0.01 to 10 wt. %.

In the hair growth inhibitor or depilation accelerator of the present invention, various components usually employed for the formulation are incorporated. Examples include, as well as oil components usually employed as components of a cosmetic composition, surfactants, purified water, alcohols, chelating agents, pH regulators, antiseptics, thickeners, emulsifiers, emulsion stabilizers, colorants, and perfumes, ultraviolet absorbers, skin whitening cosmetics, wrinkle soothing agents, humectants, regulators of sebum excretion, softeners, keratin protectives, drug efficacy ingredients, antioxidants and solvents. By mixing these components as needed, cosmetics, drugs for external application and quasi drugs can be formulated.

To the hair growth inhibitor or depilation accelerator of the present invention, a keratolytic agent or a component having hair-growth controlling or depilatory action such as thioglycolic acid or a salt thereof can also be added as needed. Examples of the keratolytic agent include lactic acid, bioprase, salicylic acid, glycolic acid, citric acid and malic acid. Examples of the salt of thioglycolic acid include not only sodium salt, potassium salt and ammonium salt but also alkanolamine salts such as monoethanolamine, diethanolamine and triethanolamine. Each of these keratolytic agents, or thioglycolic acid or salts thereof is preferably added in an amount of 0.01 to 10 wt. %, particularly 0.05 to 5%.
 

Claim 1 of 9 Claims

1. A method for accelerating depilation, which comprises: applying to the skin and hair, a depilation accelerating effective amount of a composition comprising an aqueous alcohol solution extract of Perillae herba to accelerate depilation of said hair to which said composition has been applied; and depilating said hair to which said composition has been applied.
 

____________________________________________
If you want to learn more about this patent, please go directly to the U.S. Patent and Trademark Office Web site to access the full patent.