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Title:
Polarized scorpion venom solution and a method for making polarized
scorpion venom solution
United States Patent: 8,097,284
Issued: January 17, 2012
Inventors: Mikaelian;
Arthur (Beverly Hills, CA)
Appl. No.: 12/270,664
Filed: November 13, 2008
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Executive MBA in Pharmaceutical Management, U. Colorado
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Abstract
Various embodiments of this invention
disclose a polarized dilute blue scorpion venom solution, a method for
making a polarized dilute scorpion venom solution, and a method for
administering dilute scorpion venom solution. The polarized dilute
scorpion venom solution relieves pain, improves immune-system response,
treats cancer, prevents cancer, improves quality of sleep, reduces
inflammation, and minimizes negative biological response to chemotherapy
and radiation treatment.
Description of the
Invention
BRIEF SUMMARY OF THE INVENTION
To minimize the limitations in the prior art, and to minimize other
limitations that will become apparent upon reading and understanding the
present specification, the present invention discloses a polarized dilute
blue scorpion venom solution.
One embodiment of this invention is a solution, comprising: a blue
scorpion venom; and a distilled water; wherein the solution is polarized.
The solution also relieves pain, reduces inflammation, boosts the immunity
response, prevents cancer and tumor growth, treats cancer, reduces tumor
growth, minimizes negative biological response to chemotherapy and
radiation treatment, increases appetite and body mass during chemotherapy
and radiation treatment, and improves the quality of sleep.
Another embodiment of the invention is a method of magnetically polarizing
blue scorpion venom, comprising the steps of: diluting a blue scorpion
venom in a distilled water to create a dilute scorpion venom solution;
circulating the dilute scorpion venom solution through an one or more
plastic tubes; placing a series of flat magnets along the one or more
plastic tubes in pairs and on an one or more opposite sides of the one or
more plastic tubes, wherein the series of flat magnets are aligned so that
an one or more negative poles and an one or more positive poles of the
series of flat magnets mirror one another such that the series of flat
magnets repel one another; compressing the series of flat magnets together
with a clamp so that the series of flat magnets remain in place, wherein
the series of flat magnets that are compressed together also compress the
one or more plastic tubes such that the dilute scorpion venom solution is
forced to flow through the one or more plastic tubes in close proximity to
the series of flat magnets; and repeating the circulation step until the
dilute scorpion venom solution is polarized. The polarized scorpion venom
solution treats pain, reduces inflammation, prevents cancer and tumor
growth, and treats cancer.
Another embodiment of the invention is a method of administering a blue
scorpion venom, comprising the steps of: diluting the blue scorpion venom;
polarizing the dilute blue scorpion venom; and administering the polarized
dilute blue scorpion venom to humans. The blue scorpion venom is
administered to humans orally. The blue scorpion venom reduces pain,
reduces inflammation, prevents and treats cancer, boosts the immune system
of a humans, and boosts the level of available energy.
An object of the present invention is to provide a scorpion venom solution
that relieves pain, reduces inflammation, boosts the immunity response,
prevents cancer and tumor growth, treats cancer, reduces tumor growth,
minimizes negative biological response to chemotherapy and radiation
treatment, increases appetite and body mass during chemotherapy and
radiation treatment, and improves the quality of sleep.
Another object of the present invention is to provide a method of
polarizing a blue scorpion venom solution that relieves pain, reduces
inflammation, boosts the immunity response, prevents cancer and tumor
growth, treats cancer, reduces tumor growth, minimizes negative biological
response to chemotherapy and radiation treatment, increases appetite and
body mass during chemotherapy and radiation treatment, and improves the
quality of sleep.
Another object of the present invention is to provide a polarized dilute
blue scorpion venom solution that is safe, effective, easy to make, and
easy to administer.
Another object of the present invention is to provide a polarized dilute
blue scorpion venom solution that may be used by a wide variety of people
regardless of their body size or individual characteristics.
Discussion on Safety. Dilute blue scorpion venom solution has been shown
to be safe in numerous clinical trials. A fundamental different between
necrosis and apoptosis is that in scientific studies necrosis has always
been shown to produce an inflammatory response. Apoptosis does not produce
an inflammatory response. In twenty-eight years of study of blue scorpion
venom, it has never been shown to produce an inflammatory response in
adequate dosages. However, blue scorpion venom has been shown to slow or
reverse the growth of tumors with an 89.5% success rate. From this it may
be concluded that blue scorpion venom produces apoptosis in cancer
patients. Blue scorpion venom is a land-breaking innovation in the fight
against cancer. The primary reason for this conclusion is that blue
scorpion venom has undergone an eight year Third Stage clinical trial
involving 8,302 people, which showed that blue scorpion venom has no
negative side effects, yet has an 89.5% success rate with cancer patients.
This is unprecedented is the field of oncology. In addition, because blue
scorpion venom has shown extremely potent analgesic and anti-inflammatory
effects. Blue scorpion venom works as an extraordinary compliment to
traditional therapy including: surgery; chemotherapy; radiation; hormone
therapy; and other conventional treatments.
The following is a summary of the eight year, 8,302 patient Third Stage
Clinical Trial. The information below is a summary of laboratory study
commissioned by the Cuban pharmacological company, Labiofirm, presented by
authors Alexis Diaz, Ph.D., Luis Morier, Yamira Caballero Lorenzo, Sergio
Luis Yzquierdo Silverio, Sergio Luis Maestre Mesa, Ph.D.
Pre-clinical and clinical trials have shown that blue scorpion venom is
safe and has no toxic side effects. High concentrations of blue scorpion
venom were administered in pre-clinical trials repeatedly over an extended
period. Even with high concentrations of blue scorpion venom no negative
side effects were observed. During these pre-clinical trials, scientists
recorded the following clinical signs to indicate the effect of blue
scorpion venom. These clinical signs include: Normal Motor Activity;
Healthy Reflexes; Response to Pain; Salivation; Sedation/Healthy Sleep;
Responsiveness; Condition/Appearance of the Skin; Condition/Appearance of
Mucous Membranes; Condition/Appearance of the Eyes; and Condition/Health
of Internal Organs. Over the course of this study, all participants
remained healthy. They maintained healthy weight and levels of activity.
No harm was indicated to any of the internal organs of those who
participated in the study and all were in healthy working order. In
summary, it was scientifically determined that blue scorpion venom has no
toxic side effects.
DETAILED DESCRIPTIONS OF THE INVENTION
In the following detailed description of the preferred embodiment,
reference is made to the accompanying drawings that form a part hereof,
and in which is shown, by way of illustration, a specific embodiment in
which the invention may be practiced. It is to be understood that other
embodiments may be utilized and structural changes may be made without
departing from the scope of the present invention.
In the following detailed description of various embodiments of the
invention, numerous specific details are set forth in order to provide a
thorough understanding of various aspects of one or more embodiments of
the invention. However, one or more embodiments of the invention may be
practiced without these specific details. In other instances, well-known
methods, procedures, and/or components have not been described in detail
so as not to unnecessarily obscure aspects of embodiments of the
invention.
This invention discloses a polarized dilute blue scorpion venom solution,
a method for making polarized dilute blue scorpion venom solution, and a
method to administer polarized dilute blue scorpion venom solution to
humans. As preferred, the active ingredient in the solution is the venom
of Rhopalurus junceus (blue scorpion). The venom is preferably extracted
from a bioterium of scorpions (Rhopalurus junceus--blue scorpion) in order
to obtain the quantity of venom necessary to produce an organic, natural,
and health supplement. The bioterium preferably houses at least ten
thousand (10,000) blue scorpions.
Scorpion acquisition and involved professional safety should be
considered, and the preferred method is disclosed below. In addition, the
captivity, handling, and feeding techniques are described, as well as the
method and equipment used for venom extraction. Because scorpions are
fragile and somewhat dangerous, a safe methodology to handle the animals
is preferred. Scorpion acquisition is preferably done by professionals
with over 15 years experience in the acquisition, study, and maintenance
of scorpions in bioteriums. Regular and appropriate feeding of the animals
should be maintained, along with regular cleaning of cages. Consequently,
the survival of the animals preferably exceeds multiple venom extractions.
Controlled handling and more appropriate maintenance of the scorpions will
allow for higher survival rates, and better yields of venom.
Scorpion acquisition, preferably, starts in Haiti. The blue scorpions
should then be imported to the bioterium. This first generation of
scorpions is preferably transported in protected units so that they will
be unable to escape into the environment. Animal quarantine will be done
by the rules and regulations as set forth by the country into which the
bioterium is set up. All necessary tests indicating the health of the
scorpions should be obtained through the appropriate ministries of the
importing country.
Personnel safety. The bioterium staff should be issued protective rubber
gloves which will be impossible for the sting of Rhopalurus junceus (blue
scorpion) to penetrate. The staff is preferably required to wear this
protective gear whenever they are in contact with the scorpions or on the
grounds of the scorpion bioterium, thereby protective themselves from
injury. A LD 50 value of 8.0 mg/kg has been reported for the blue scorpion
species. This indicates that the blue scorpion species is not among the
most venomous scorpions. This is a common scorpion in Haiti, and many
people are stung each year. The only deaths that have been reported are
attributable to anaphylactic shock following a hypersensitivity immune
reaction. Though the sting of Rhopalurus junceus (blue scorpion) is
non-fatal and rarely elicits a severe physical reaction, in case of a
highly unusual allergic reaction to the bite, medication and antidote are
preferably present and available at the scorpion bioterium at all times.
Environmental Safety. The acquired blue scorpions should be imported
utilizing sealed, perforated boxes which will allow the scorpions
sufficient air without providing any opportunity for escape. Once
transported to the bioterium, the scorpions should be carefully
transferred individually into cages, preferably 50 centimeters wide by 75
centimeters long by 40 centimeters high in size, and made of light colored
polyethylene for easy visual monitoring. However, the cages can be of any
size, material or color without deviating from the scope of this
invention. The corners of the boxes will be covered with plastic adhesive
tape. This tape will prevent any scorpions from escaping. These cages will
be stored a significant distance from any exits to the building so that in
the highly likely case that a scorpion should leave its cage, the
bioterium technicians will be able to see the animal before it has the
possibility of escaping. Finally, each cage will be numbered with a count
of the scorpions for that cage. This count will be verified at the
beginning and end of each day to ensure that the correct number of
scorpions is encaged and that there are no escaped animals.
Animal Safety. From acquisition to transportation to deposition in the
bioterium, every effort should be made to ensure the safety and minimized
stress of the animals. This is important because a stressed scorpion may
not deliver as high a quality of venom. Great care should be made to
ensure that excessive movement does not occur of the travel containers
holding the scorpions. Once deposited in the bioterium, the scorpions
should be regularly monitored for health and levels of stress. Their cages
should include natural items such as earth, sand, and bricks to better
replicate a natural environment. Cages should be regularly cleaned and the
scorpions fed a nutritious, all-natural diet.
Bioterium of scorpions preferably consists of one area covering twelve
(12) square meters, and is preferably designed to keep spiders, scorpions,
and insects in place and safe. The room should be equipped with several
windows that provide natural ventilation; heaters should be turned on
during colder months to maintain the temperature between 23-25.degree. C.
The animals, which arrive in the bioterium, are identified and selected:
adult specimens, ready for venom extraction, are accommodated in
appropriate cages according to first, second, third extraction, and so on.
All the activities should be supervised and controlled by a professional
in order to obtain satisfactory results. Birth of young in the captivity
is common. If there is a possibility of raising them, it is necessary to
isolate the females and their progeny, and then the young from the mother.
The animals used in the venom production should be kept in different
cages. In order to maintain a productivity control, the animals from
different extractions should never be mixed. Preferably the cages allow
for easy visual monitoring. Typically, commercially available boxes have
rough corners that allow animals to escape. To avoid this, the corners are
covered with plastic adhesive tape. The cage floor is preferably covered
with a plate of waved cardboard to offer comfort to the animals and avoid
unnecessary stress. Layers of waved cardboard that are overlaid and folded
in accordion shape, increase the surface area of the habitat and avoid
excessive contact among the animals, preventing frequent cannibalism.
Cardboard offers appropriate protection since the scorpions show a high
night activity. Further, cardboard is an extremely light material,
avoiding wound to the animals during handling. It is also cheap and easy
to find in the market. Water is supplied in plastic bowls (one in each
cage), containing wet cotton. The cages are placed on iron shelves and
covered with net lids framed with wood; they should be labeled
accordingly. A control file should be kept beside each cage and data such
as entrance date, feeding, extraction, and death are registered.
Maintenance is preferably performed weekly, and includes change of cotton
and cardboard, removal of dead animals and wash of each one of the boxes
with water and neutral soap. Daily handling should be avoided in order to
decreasing animal stress. Other substrates such as earth, sand, bricks,
and roof tile may also be used to imitate the natural habitat of the blue
scorpion.
Feeding. The bioterium should be stocked with several kinds of insects to
feed all the animals in the bioterium. Food is offered to the scorpions
once a week, after venom extraction, preferably consisting of Gryllus sp.,
Periplaneta americana, or Pycnocellus sp. (common roaches and crickets).
The insects are kept in the cages for two days and then the cleaning is
performed, removing all animals, washing the cages with water and neutral
soap, and changing cotton and cardboard. Every week, specimens from two or
three cages are fed according to the food availability, assuring that each
cage receives food at least every forty (40) to fifty (50) days a year.
The quantity of food is calculated according to the quantity of scorpions
in each cage: preferably a roach for every two animals, or an adult
cricket for every animal.
Venom extraction is preferably performed every month. The scorpions should
be milked for their venom on a monthly basis, preferably, by highly
trained staff. The venom is extracted by a mild electro-shock placed
briefly on the tail of the scorpion which encourages the scorpion to
release its venom. This shock causes no physical damage to the scorpion,
nor does it shorten the life span of the scorpion. The venom is then
collected into a small cup and placed in refrigerated storage to maintain
the quality of the venom. Food is given a week after venom extraction in
order to allow time for the animals to recover from any stress associated
with the venom extraction. If they are fed before the extraction, the
quantity of venom produced can be affected.
Storage and transportation of the venom. Once extracted, the venom is
preferably kept in a locked refrigeration unit. Preferably, the venom is
regularly transported from the bioterium to a production facility. If the
production facility is in the United States it should be an FDA licensed
production facility. When transported, the venom is preferably maintained
in a temperature controlled, double-sealed container for added safety and
to maintain venom quality.
Production of the dilute scorpion venom solution.
As noted above, the first stage of production of the dilute scorpion venom
solution of the present invention is extraction. Individual "crops" of
scorpions are extracted every 30 days. These crops are kept separated from
one another, but are given the same diet. This consistency in diet, timing
of extraction, and population control is intended to support consistency
of concentration of venom per each extraction.
Preferably, a one hundred milliliters (100 ml) glass container. The
container can be empty, as preferred, or filled with of medical distilled
water, which is used for extraction. Using electrical stimulation of each
scorpion's tail, drops of scorpion venom will be captured in this 100 ml
glass container. Into each 100 ml container, approximately two hundred
(200) drops of venom are extracted with an average of 2.55 drops from each
scorpion.
The second step is transportation. Once extraction is completed, the
container is sealed and placed into a refrigerated environment. The
container should be kept in that refrigerated environment for thirty
minutes until the venom reaches a maximum of twelve degrees centigrade (12
C (52 F)). At that time, the container should be packed into a
refrigerated compartment which keeps an even temperature range between 12
and 14 C (52-58 F) for 48 hours. These times and temperatures are
preferred, but a wide variety of times and temperatures are acceptable
without deviating from the scope of the invention.
The third step is receiving. The manufacturing (preferably pharmaceutical)
laboratory receives the concentrated venom solution. This concentrate
should be brought to the laboratory facility. This concentrate should be
received in individual containers ranging in size from 100 ml to 500 ml.
The fourth step is initial storage. The laboratory must immediately
refrigerate the concentrate. As noted above, the concentrate is preferably
received by the laboratory in a refrigerated container. Concentrate is
preferably refrigerated and maintained at a range between 12 to 14 C (52
F-58 F). The concentrate degrades at an accelerated rate when exposed to
bright light; as such, this refrigerated storage environment should be
protected from light and without internal illumination.
The fifth step is filtration. Scorpion venom is a complex mixture of
salts, small molecules, peptides, and other proteins. The laboratory
should filter the venom using glass fiber membrane filter that is
preferably 0.80 .mu.m, 25 mm, 1 pk/50 pcs. This ensures the sterilization
and purification of the venom. The venom from a crop of scorpions is
extracted and filtered into a single, sterilized glass container.
The sixth step is bulk manufacturing. After filtration, the venom is
combined with chilled, medical-quality distilled water to achieve a
specifically maintained concentration within a sterilized environment. A
bulk version of the product is transferred into a sealed, sterilized bulk
container and the container then transferred into to a refrigerated
environment.
Determining the concentration. Typically, the dilute blue scorpion venom
solution contains 0.0003 ml of venom per 0.9997 ml of distilled water
(totaling 1 ml of prepared dilute solution) for treatment of third and
fourth stages of cancer. Concentration for treatment of baseline, first,
and second stages of cancer is preferably 0.00025 ml of venom in 1 ml of
prepared dilute solution.
The final bulk dilute solution is preferably stored and shipped in a dark
and refrigerated environment.
The venom has tendency to separate from water when suspended in water for
an extended period of time. To achieve consistent concentration of venom,
the sealed bulk container is preferably agitated in a back and forth
manner for no less than 30 minutes before being transferred into
individual containers. During the packaging process the bulk container
should be continuously agitated through stirring.
The final step of the process is packaging and bottling. The bulk product
is transferred in a sterilized environment into individual one liter
bottles, which should include labels, air-tight seals, and opaque
containers, which protect the product from degradation due to
inappropriate exposure to light. The containers are pre-sterilized before
being filled with the product. The process of packaging is time sensitive.
Undo exposure to air and excessive temperatures will undermine the potency
of the venom. As such, time is a sensitive issue with the product. Exposed
to room temperature, the process cannot be extended past a few
(approximately four) hours from removal from refrigeration to completion
of bottling. However, if bottling is done in a highly air conditioned
environment (lower than 15 C or 58 F) or if the distilled water used in
production is chilled (through prior refrigeration) then the period of
production from removal from refrigeration to finalized bottling can be
extended. Eight (8) hours for highly chilled distilled water; twelve (12)
hours for highly refrigerated environment.
Once the bottling procedure is complete, bottles of final product are to
be stored in a dark, refrigerated environment maintained, as preferred, at
a temperature between 12 and 14 C (52 F and 58 F) where they will wait
until final shipping.
The dilute blue scorpion venom is preferably tested for bacterial
contaminants, chemical contaminants, and concentration. Standard microbial
and mass spectrometry tests are preferably used. If possible, no product
should be shipped to a customer until the batch has undergone testing for
purity.
Standard testing procedures, such as Lowry's method for determining
protein concentration should be used to quantitatively evaluate the dilute
solution. Other types of procedures, known in the art, may also be used.
Batches should be rejected if bacterial or chemical contaminants are
found, or if more than 5% of the bottles test for levels of any chemical
naturally found within the venom, but at a higher or lower concentration
in excess of 10% deviation from the standard concentration per
standardized mass spectrometry of the venom.
Polarization of the dilute scorpion venom solution. Preferably, the dilute
solution is polarized. The preferred process for polarizing blue scorpion
venom is the Mikaelian Polarized Liquid Process, named after the current
inventor. The first steps in the polarization process, preferably, are to
circulate the dilute scorpion venom solution repeatedly through plastic
tubes. Preferably the plastic tubes are one and a half (1.5) centimeters
in diameter, but they can be any diameter, and can be made from any
malleable, non-metallic material. The circulation is performed by one or
more small pumps. The next step of the process is to place, along the pump
or tubes, a series of flat magnets. Preferably these magnets are placed in
pairs along the opposite sides of the tubes and are aligned so that the
negative poles and positive poles of the magnets mirror one another so
that the magnets repel one another. The magnets are then compressed with
one or more non-metallic, preferably wooden, clamps so that the magnets
remain in place. The magnets are compressed to within two millimeters of
one another, also compressing the tubes so that the water must flow
through a small gap between the magnets. Two millimeters is a preferred
compression point, any greater or lesser compression point may be used, so
long as the liquid can flow within the tube, without deviating from the
scope of the invention. Preferably, the scorpion venom dilution is
circulated through this tube lined with pairs of magnets for an extended
period of time. The resulting polarized liquid, compared to non-polarized
liquid, is absorbed far more rapidly into the human and is significantly
more bio-available on a cellular level, resulting in significantly
improved results.
FIG. 5 (see Original Patent), discussed below, discloses a study that
showed how polarized liquid is absorbed more rapidly into the body. The
efficacy of polarized liquid has been tested in small scale blind studies
in which the subjects did not know whether or not they were receiving
unpolarized liquid or polarized liquid. In those cases where individuals
received polarized/magnetized liquid, they reported significantly improved
results. The effects of this Mikaelian polarization process stays
effectively within the liquid for three to four weeks before the liquid
returns to a state similar to pre-polarization. The Mikaelian polarization
process works through repeated exposure to fixed magnetic fields that
align the magnetic poles of the molecules within the scorpion venom liquid
in such a way that it forms a geometric consistency between the molecules
which influences the body's ability to recognize the liquid and open
molecular gates for better absorption. Typically fixed magnets are used
however, electromagnets may also be used.
FIG. 1 (see Original Patent) is an illustration of the results of a study
that shows the effectiveness of blue scorpion venom as a pain killer. Blue
scorpion venom is a highly effective pain killer. In this study, several
groups were given different amounts of blue scorpion venom. Another group
was given a powerful, clinically used analgesic (paracetamol). Another
group (a control group) was not given anything. As shown in FIG. 1,
compared to the control group (which received no pain killer), those
participants who were given paracetamol had 47% less pain. However, those
given high concentrations of blue scorpion venom had 55% less pain than
those who were not given any pain killers. Thus, it may be concluded that
blue scorpion venom diminishes pain by 55%.
FIG. 2 (see Original Patent) is an illustration of the results of a study
that shows the effectiveness of blue scorpion venom as an inflammation
reducer. Blue scorpion venom, as shown in FIG. 2, relieves inflammation.
In the study, scientists created three groups. One group was given an
anti-inflammatory steroid, (dexamet) often given to cancer patients after
chemotherapy. Another group was not given anything. A third group was
orally given blue scorpion venom. All three groups had inflammation
artificially induced and were then observed. The level of inflammation was
recorded by weighing the participants before and after inflammation was
induced. Compared to the control group that received nothing, those who
received blue scorpion venom had up to 38% less inflammation. From this
information, may be concluded that the blue scorpion venom solution of the
present invention, significantly reduces inflammation. Additional
information from other clinical trials strongly suggests that at higher
dosages than were administered in pre-clinical trials, blue scorpion
venom's anti-inflammatory activity is even more powerfully enhanced.
FIG. 3 (see Original Patent) is an illustration of the results of a study
that shows the effectiveness of blue scorpion venom as a cancer fighter.
As a part of the study, cancer cells from four different types of cancer
were put in test tubes and then exposed to blue scorpion venom. For all
types of cancer used in the study, the number of cancer cells decreased
after being exposed to blue scorpion venom. One group decreased by 60% in
just one week of exposure.
FIG. 4 (see Original Patent) is an illustration of the results of a study
that shows the effectiveness of blue scorpion venom as a cancer treatment
in the body. As shown in FIG. 4, five groups had cancerous tumors. One
group (the control group) was not given anything. The other four groups
were given different levels of blue scorpion venom. After several weeks,
the size of the tumors was assessed. The tumors in those who received high
concentrations of blue scorpion venom were 45% smaller than the tumors in
those which received no blue scorpion venom. From this data, it may be
concluded that blue scorpion venom inhibits the growth of cancer cells in
a living organism.
FIG. 5 (see Original Patent) is an illustration of the results of a study
that shows the efficacy of the Makaelian Polarization Process.
Horizontally the graph in FIG. 5 represents 24 day testing with urine
samples. Vertically the graph in FIG. 5 represents the percentage of
unabsorbed minerals and supplements in urine.
An introduction to the Mikaelian Polarized Liquid (MPL) process.
The human body is composed of about 70% water and 30% solids. Normal
metabolic activity can only occur when cells are at least 65% water. Water
is the most important nutrient because it is responsible for so many
functions and for the activation of cellular functions by other nutrients.
When nutrients have reached the cells, water is necessary for the cells to
function, maintain (catabolic phase) and build and repair (anabolic)
phase. These two phases of cellular function are closely related to the
cellular water flow or lack of its flow.
Intra-Cellular & Extra-Cellular. There are two types of water in the body,
intra-cellular and extra-cellular. Extra-cellular is the fluid outside an
individual cell while intra-cellular is the fluid found inside the cell.
Both of these types of water are necessary for optimal health or wellness
of every cell in the body. In order for the cells to be biologically
active they must absorb water. When the cells over-hydrate it triggers an
anabolic phase, one of the healing mechanisms in the body. The anabolic
phase is triggered by a positive hydrogen balance, protein synthesis, or
growth hormone.
Studies have been performed to test whether there is increased
transportation of necessary nutrients to the cells by using a Mikaelian
Polarized Liquid in order to improve the effectiveness of supplements and
medications. The primary goal in this clinical study was to evaluate
whether or not drinking Mikaelian Polarized Liquid with vitamins and
minerals every day will increase delivery of nutrients to cells by
increasing cellular hydration as a fundamental indicator of wellness. Each
subject was evaluated for baseline numbers on the first day of the study.
Each subject was retested on the fifteenth and the thirtieth day of the
study. At each office visit we performed: analysis, height, weight,
temperature, blood pressure and pulse in addition to urine, blood and
saliva samples. Each subject was provided with an instruction sheet
indicating how much Mikaelian Polarized Liquid to consume with each intake
of vitamins and minerals. Changes in cellular hydration involve a
proprietary combination of specific measurement parameters based on a
mathematical formula to understand any negative deviation, with an
emphasis on surface tension, specific gravity and resistivity measurements
of urine, blood and/or saliva, for each subject in the study.
Conclusion of study. Upon completion of this wellness study it has been
indicated that overall these test subjects showed a 27.5% increase in
hydration and 58% increase in mineral absorption at a cellular level. The
individual's percentages vary from 18-23.5% but all the subjects show
significant increase in these wellness hydration levels per the specific
method of testing cellular hydration. This study validates that a
Mikaelian Polarized Liquid increases mineral and supplement absorption at
the cellular level.
Technical details on the Mikaelian Polarized Liquid process.
The first step is determining the correct position of magnetic poles. It
is required to have a regular compass for magnets pole determination.
Position a compass on the table next to each magnet. The needle of the
compass will point to the north pole of the magnet. The needle of the
compass is positively charged, thus, it is attracted to the negative pole
of the magnet, allowing for identification of that pole. The one of the
sides of the magnet that will be used for polarization is slowly moved
towards positively charged needle. If highly attracted, the compass needle
indicates that it is the negative pole of the magnet. This will be used
for identification. The north pole of the magnet is physically marked as a
(minus) pole or negative charged. The needle of the compass is positively
charged, thus, it is repulsed by the positive pole of the magnet, allowing
for identification of that pole. The opposite side of the magnet that will
be used for polarization is slowly moved towards the positively charged
needle. If highly repulsed, the compass needle indicates that it is the
negative pole of the magnet. This will be used for identification. The
south (positive) pole of the magnet is physically marked in red or with
plus sign to indicate that it is positively charged.
The second step is preparation of hose and magnetic sandwiches. Two wooden
panels of the dimensions ten (10) centimeters in height, one (1)
centimeters in width, and sixty (60) centimeters long are prepared. The
panels can be of any dimension and any non-metallic material without
deviating from he scope of the invention. A line of industrial strength
magnets are glued to these panels using a strong epoxy resin. The magnets
are affixed to the vertical center of the panel in a straight line. The
negative/north/minus pole of the magnet is glued face down to the panel.
The positive/south/plus pole of the magnet is face up and exposed. The
magnets are lined in succession and preferably have no spacing between
their edges. A plastic transparent hose two (2) meters in total length is
glued to the vertical center of one of the line of magnets on the wooden
panels. The hose extends approximately seventy (70) centimeters from
either side of the wooden panel. The hose may be opaque and made out of
any non-metallic pliable material without deviating from the scope of the
invention. Four holes are drilled in each of the panels. One pair of holes
is situated on end of the length of the panels; another pair of holes on
the opposite end of the length of the panels. The two panels are made to
face one another. They are connected by four bolts which are threaded
through the four pairs of holes on either side of the panel. Threaded
around each bolt is a spring to provide resistance while tightening the
bolts. The bolts are tightened to a point where the wooden panels are
compressed to a preferred distance no less than 3 mm in separation,
compressing the plastic transparent hose in the process.
The third step of the process is connection of hose, pump, and receptacle.
One end of the hose affixed to the magnetic sandwich is connected to an
electric pump. The other end of the hose is deposited in a container. From
that container the end of another hose of equal diameter is placed in the
container. The opposite of this hose is affixed to the electric pump. The
pump is preferably an electric pump, but may be any pumping or actuating
device that circulates the fluid.
The fourth step is recirculation. The container is filled with distilled
water or a mixture of distilled water and scorpion venom or a mixture of
distilled water and nutrients or a mixture of distilled water, nutrients,
and scorpion venom. The pump is turned on and the liquid is made to
recirculate from the container, through the magnetic sandwich to the pump
and then back to the container at a rate of approximately 190 gallons per
hour. This process of recirculation is repeated at length and will vary
based upon the amount of liquid being polarized. The greater the amount of
liquid; the longer the process of polarization is. The lesser the amount
of liquid; the shorter the process of polarization is.
Intense Magnetic Resistance (IMR). The unique element of Mikaelian
Polarized Liquid is creation of Intense Magnetic Resistance (IMR) by
utilizing similar poled/charged sides of magnets at very close distances.
Other forms of polarization utilize magnetic attraction, while Mikaelian
Polarization Process utilizes magnetic repulsion as a mechanism for
polarization. Liquids flowing through Intense Magnetic Resistance (IMR)
fields are subject to molecular polarization which strongly affects the
geometric relationships between molecules and the electromagnetic fields
surrounding those molecules in a way which is commercially significant.
Polarization enhances utilization of water and nutrients. The realignment
of magnetic poles of molecules using Intense Magnetic Resistance (IMR)
enhances absorption and utilization of water, nutrients, and scorpion
venom on a cellular level. In particular, the cell membranes of cancer
have a distinctive and excessive negative electromagnetic charge. The
polarization of liquid allows for the molecules within the liquid to be
utilized with extreme efficiency by cancer cells, as the positive
electromagnetic poles of these molecules are thoroughly attracted to the
excessive negative charge of cancer cell membranes. Specific to this
application, the utilization of scorpion venom molecules leads to a rapid
and efficient triggering of apoptosis (programmed cellular suicide) within
cancer cells; thereby accelerating their death and inhibiting the growth
of cancerous tumors.
Additional information on the cancer fighting ability of blue scorpion
venom.
Several studies have shown the efficacy of blue scorpion venom in treating
and fighting cancer. One of these studies, as discussed above, was a third
stage clinical trial involving eight thousand three hundred and two
(8,302) patients. In this study, 8,302 patients of a variety of different
stages of cancer were given blue scorpion venom. A variety of cancers were
studied with breast, brain, lung, prostate, and colon cancers being the
most common studied. Cancers of the larynx, lung, and uterus showed the
greatest benefit over the course of the study.
The researches of the trial used summaries of the clinical history of each
patient issued by the doctor who tracks the patient through different
medical institutions. Each patient was evaluated monthly. During the
evaluation, doctors spoke with the patient or a close family member and
organized their records according to the type of neoplasia (abnormal cell
growth).
The conclusions of this study are staggering: no side effects occurred
from taking this natural product; and 89.55% of patients experienced an
improved quality of life from taking blue scorpion venom.
The Eastern Cooperative Oncology Group (ECOG) has a set up a widely
recognized scale to determine the quality of life of a cancer patient
enrolled in a clinical trial. Grade description: "0"=capable of carrying
out a normal physical activity without restrictions; "1"=symptomatic, but
not hospitalized (restriction on vigorous physical activities, but an
outpatient and able to undertake light chores or those of a sedentary
nature); "2"=in bed less than 50% of the time, not hospitalized, able to
care for self, but unable to work more than 50% of the time when out of
bed; "3" capable of personal care, but confined to a bed or chair more
than 50% of the time; "4"=completely incapable of any effort, totally
confined to bed; and "5"=death.
FIG. 6 (see Original Patent) is an illustration of the results of a study
that shows the quality of life for larynx cancer patients that used blue
scorpion venom. As shown in FIG. 6, over 78% of the larynx cancer patients
were asymptomatic (0 on the ECOG scale) or only mildly symptomatic (1 on
the ECOG scale).
FIG. 7 (see Original Patent) is an illustration of the results of a study
that shows the quality of life for lung cancer patients that used blue
scorpion venom. As shown in FIG. 7, over 70% of the lung cancer patients
were in ECOG categories 0, 1, and 2.
FIG. 8 (see Original Patent) is an illustration of the results of a study
that shows the quality of life for uterine cancer patients that used blue
scorpion venom. As shown in FIG. 8, over 65% of the uterine cancer
patients were in ECOG catagories 0, 1, and 2.
FIG. 9 (see Original Patent) is an illustration of the results of a study
that shows the survival rates for the sample types of cancer for patients
that used blue scorpion venom. As shown in FIG. 9, the survival rates of
the cancer patients that used blue scorpion venom was extremely high. Over
95% of larynx cancer patients, over 80% of lung cancer patients, and over
94% of uterine cancer patients survived during the course of the study.
This study shows a substantial improvement for cancer patients that used
blue scorpion venom as part of their cancer treatment regimen. Overall,
89.55% of patients in this eight-year clinical trial achieved an
improvement in health and quality of life through taking blue scorpion
venom, independent of what stage of cancer they were subject.
Current scientific research. Since the above mentioned clinical trial,
additional independent studies, including studies conducted by the present
inventor, have been conducted. This additional research validates previous
results achieved by past research and the clinical trial discussed above.
Although blue scorpion venom is clearly effective, not all people benefit
equally from using blue scorpion venom. Some individuals immediately get
well, whereas others show no signs of improvement. The additional research
has developed several criteria to systemize all possible aspects which
influence the effectiveness of blue scorpion venom. These factors are the
result of empirical studies, and they lead to the following conclusions as
in which patients blue scorpion venom tends to have greater benefit.
Current research has found that, independent of stage of cancer, it is of
greater benefit to begin using blue scorpion venom as soon as is possible.
Delaying onset of starting blue scorpion venom has not been shown to be
beneficial.
Metastasis. Blue scorpion venom has shown the greatest benefit for those
whose metastasis has not expanded to include (and heavily compromise the
function of) major vital organs. Blue scorpion venom still shows benefit
for those whose metastasis has included major vital organs; however,
additional factors become significantly more important in these cases.
Blue scorpion venom appears to have greater benefits to those patients
whose cancer has not metastasized. Though blue scorpion venom still has
shown amazing results with those patients whose cancer has metastasized,
the type of metastasization will influence the degree of effectiveness of
blue scorpion venom.
Additional complicating health conditions. Independent of whether a
patient's cancer has metastasized, those patients who do not have
additional chronic health issues have been shown to have more pronounced
benefits. Chronic non-cancer health issues effecting vital organs (i.e.
diabetes, cirrhosis, thyroid disease, etc.) tend to more greatly limit the
full benefit of blue scorpion venom than chronic conditions which do not
affect major vital organs. Blue scorpion venom has generally been shown to
be effective even in these cases; however, once again, additional factors
take on a heightened degree of importance.
Ongoing exposure to environmental toxins. The root cause of many cases of
cancer is over-exposure to any of various carcinogenic toxins found in our
environments. If a person's cancer is rooted in the exposure to
environmental toxins, it very important for blue scorpion venom's efficacy
that a person remove their self from that high-toxicity environment.
Otherwise, the root cause of their cancer will continue to be supported
and the benefit of Blue scorpion venom will be limited.
Genetics. Some cancer patients have a genetic (family) history of cancer.
These genetically-influenced cancers are often triggered by certain
environmental and stress-based factors; however, the very genetic
influence of these cancers often limits the effectiveness of blue scorpion
venom. Blue scorpion venom is still highly beneficial in these cases, but
additional conditions need to be addressed. In addition, for those who are
highly genetically susceptible to the development of cancer, blue scorpion
venom has shown great promise as a preventative measure.
Psychological/environmental stress. Research has found that clients under
significant amounts of psychological and/or environmental stress tend to
have greater challenges with their recovery from cancer than those who are
able to overcome their psychological stress and/or separate their self
from extreme environmental stress. Blue scorpion venom has been found to
more beneficial for those patients who through life choices, changes in
lifestyle, and/or counseling are able to limit or overcome excessive
psychological/environmental stress. Additionally, endocrinologic and
immunologic rationales for a susceptibility to cancer in depressed
patients have been proposed. These theories suggest that stresses, such as
depression, lead to excesses of hormones including adrenal
corticosteroids. It is through these corticosteroids that
immunosuppression is mediated. Evidence for this in humans includes
findings of increased levels of corticosteroids in depressed patients and
lymphocyte suppression in bereaved patients compared to non-depressed
subjects. Patients with compromised immune systems have been shown to have
higher rates of cancer.
Dietary/nutritional factors. Nutrition and diet play a key role in the
development of many cancers. Nutritional deficiencies and dietary
imbalances (excessive saturated fat, lack of fiber, excessive chemical
additives, etc.) have been shown to influence the development of cancer.
It is essential for the benefit of a blue scorpion venom user that they
maintain a healthy, balanced diet which is conscious of their condition.
Blue scorpion venom users who continue to maintain an unhealthy, nutrient
deficient diet do not benefit from Blue scorpion venom as powerfully as
those who maintain a health conscious approach to nutrition and diet.
Psychological state/commitment to healing. Multiple studies have shown
that individuals with an optimistic outlook towards their life and healing
show better results than those who have a negative, pessimistic view
towards life and the future. Though this is not always the case, still, as
a general trend research has seen that those who are fully to their
healing tend to have more positive results than those who have given up
hope.
Additional information on how blue scorpion venom works in a patient's
Body. Research suggests that blue scorpion venom has a multi-factorial
anti-cancer effect. The key to Blue scorpion venom's success is it that it
both directly attacks cancerous cells and triggers biological responses
which are anti-cancer in nature, including apoptosis. Blue scorpion
venom's has five primary biochemical actions. First, blue scorpion venom
stimulates a person's immune system. Research has confirmed that in
patients who have been administered blue scorpion venom, an increase in
white blood cell count occurs. White blood cells are responsible for the
protective function of the immune system. With all cancers, a person's
immune system plays a crucial role. For many types of cancer, the
responsiveness of one's immune system plays the determining role in that
cancer's development. Second, blue scorpion venom inhibits angiogenesis in
cancer tumors. Research confirms that a slowing or reversal of
angiogenesis takes place for cancer tumors. It is essential for tumors to
develop new blood vessels to feed their need for growth. Without these
blood vessels, these tumors cannot expand, and frequently die off. Third,
blue scorpion venom inhibits cancer cell functionality. Research shows
that the venom Leiurus quinquestriatus of the Buthidae family of scorpions
of inhibits the functionality of sodium/potassium channels in cell
membranes. The blue scorpion (Rhopalurus junceus) is also a member of the
Buthidae family. Being of same family and possessing biochemical
similarities, deductive logic suggests that the venom of the blue scorpion
also inhibits the functionality of sodium/potassium channels in cell
membranes. All human cells require a balance of sodium and potassium ions
to function properly. Without this crucial balance, the cell becomes weak
and can die. This is the case with cancer cells exposed to blue scorpion
venom. Fourth, blue scorpion venom produces cytotoxicity in cancer cells.
Research shows that the venom Leiurus quinquestriatus of the Buthidae
family produces apoptosis in low concentrations. The blue scorpion (Rhopalurus
junceus) is also a member of the Buthidae family. Being of same family and
possessing biochemical similarities, deductive logic suggests that the
venom of the blue scorpion also produces apoptosis. This conclusion is
further supported by more recent additional research, in which cancer
cells exposed to blue scorpion venom in vitro experienced cytotoxicity.
Apoptosis is concluded because patients administered blue scorpion venom
do not experience an inflammatory response which normally occurs when
necrosis takes place. Instead, patients administered blue scorpion venom
experience a powerful anti-inflammatory response, further suggesting the
expression of apoptosis. Fifth, blue scorpion venom produces a healthy
neurological response to cancer. Research conducted and documented in the
eight-year third stage clinical trials discussed above, found that
patients taking blue scorpion venom consistently exhibited greater
sedation, improved sleep, healthy reflexes, and improved motor skills.
These responses indicate that blue scorpion venom somehow interacts with
the nervous system in healthy, regulatory way.
Multiple research beginning in the 1950's have shown a correlation between
extreme nervous system activity (excessive or deficient) and aggressive
tumor cell proliferation. By playing a positive regulatory role with the
nervous system, it is concluded that blue scorpion venom inhibits cancer
cell proliferation through the support of healthy neurological
responsiveness.
Importantly, blue scorpion venom produces cytotoxicity and inhibits cell
functionality only with cancer cells and not with healthy normal cells. In
the eight-year third stage clinical trials discussed above, patients
consistently experienced anti-inflammatory responses, diminished pain, and
improved health while cancerous tumors expressed diminished or reversed
cell proliferation. The results of the clinical trials have by
independently confirmed by additional research. Moreover, in vitro
experiments also confirm that cancer cells exposed to blue scorpion venom
experience cytotoxicity.
Blue scorpion venom produces cytotoxicity in cancer cells, but does not
produce cytotoxicity with healthy cells for two reasons. First, cancer
cells identify proteins in venom as viable nutrient. Cancer cells are
known to aggressively seek out nutrients in their environment to support
rapid cellular division. Blue scorpion venom is extremely rich in a
variety of proteins. Cancer cells may misidentify and ingest these venom
proteins far more aggressively than healthy cells, thereby creating a much
higher absorption rate. Second, cancer cell potassium channels provide
greater access to blue scorpion venom absorption. The structure of
potassium channels on cancer cells are often distinct from those of found
on healthy cells. The unique electrostatic charge of the proteins in blue
scorpion venom may be particularly drawn to the potassium channels of
cancer cells resulting in much more rapid absorption.
Blue scorpion venom as a cancer treatment. Research confirms that blue
scorpion venom is effective in treating a wide variety of cancers
including cancers of the: prostate; colon; lung; brain; digestive tract;
breast; and cervix.
Blue scorpion venom and common health benefits. Research shows that
patients administered blue scorpion venom frequently experience the
following health benefits: improved quality of life; increased survival
rate; and tumor remission lasting five or more years. 89.5% of patients
who have used blue scorpion venom in their treatment have experienced
these benefits. As stated above, these benefits are dependent upon stage
of cancer, genetic issues, condition of vital organs, continued exposure
to environmental toxicity, lifestyle choices of the patient, and other
factors.
Some initial changes in the quality of life of a patient using blue
scorpion venom include: minimized negative biological response to
chemotherapy and radiation treatment; increased appetite, as well as a
mid-term increase in body mass; improved quality of sleep; pain relief;
and improved patient immune-system response.
Administration of blue scorpion venom. Blue scorpion venom is primarily
administered orally. Some patients may also have blue scorpion venom
administered via additional different formats. Oral is the most common
form of administration. A patient may be given certain dietary
restrictions to ensure the greatest effectiveness of blue scorpion venom.
Nasal administration, through a nasal spray, is best for patients with
cancers related to the nervous and skeletal systems. This administration
also works well for patients in extreme pain. For patients with cancers
specifically related to the respiratory system, an aerosol administration
of blue scorpion venom has been shown to be most beneficial. For cancers
related to the rectum or vaginal region, specifically administered drops,
suppositories, or douches have had the best and most comfortable effect.
For patients with skin or scalp cancer, a topical ointment of blue
scorpion venom has been shown to be most effective.
The effectiveness of blue scorpion venom. Research concludes that in lung,
liver, digestive tract (in general terms), prostate, and breast cancers
there are positive clinical and laboratory responses approaching 89.5%.
Clinical response, does not mean that 89.5% of patient's have been totally
cured, rather this percentage of patients experience an improvement in
quality of life and survival, and in some cases, a total cure of the
disease.
Blue scorpion venom is uniquely effective in the fight against cancer.
Blue scorpion venom: is successful in 89.5% of cancer patients; has
undergone a Third Stage clinical trial involving 8,302 patients; has no
negative side effects; is an effective analgesic; has significant
anti-inflammatory properties; and in combinational therapy, blue scorpion
venom has been used to improve the results with surgery, chemotherapy,
radiation, hormone therapy, and other conventional treatments.
The following references provide details regarding studies and research of
the efficacy of scorpion venom. These references are incorporated by
reference herein as though set forth herein in full. Bordier C. M.,
Martinez F. M. M., Salgado S. H. L., Bory P. G. H., Perry B. F., Granado
M. R. et al. Composicion antitumoral. Certificado de autor de invencion
1995; #AGIK 35/56. Castaneda Pasaron O. Toxinas animales: Acciones
facilitadoras de la transmision colinergica. Revista Biologia 2000; 14(1):
1-15. Compton M M. A biochemical hallmark of apoptosis: internucleosomal
degradation of the genome. Cancer Metastasis Rev September 1992;
11(2):105-19. Chen, B. and Ji, Y. Antihyperalgesia effect of BmK AS, a
scorpion toxin, in rat by plantar injection. Brain Res. 2002; 952 2, pp.
322-326. De Armas L F. Escorpiones del Archipielago Cubano. 1V. Nueva
Especie de Rhopalurus (Scorpionida: Buthidae). Poeyana 1974; 136:1-12.
Dini L, Coppola S, Ruzittu M T, Ghibelli L. Multiple pathways for
apoptotic nuclear fragmentation. Exp Cell Res Mar. 15, 1996; 223(2):340-7.
Guan, R. J., Wang, C. G., Wang, M. and Wang, D. C. A depressant insect
toxin with a novel analgesic effect from scorpion Buthus martensii Karsch.
Biochim. Biophys. Acta 2001; 1549 1, pp. 9-18. Guan, R. J., Wang, M.,
Wang, D. and Wang, D. C. A new insect neurotoxin AngP1 with analgesic
effect from the scorpion Buthus martensi Karsch: purification and
characterization. J. Pept. Res. 2001; 58 10, pp. 27-35. J. I. Kourie and
A. A. Shorthouse. Properties of cytotoxic peptide-formed ion channels. Am
J Physiol Cell Physiol 2000; 278: 1063-1087.
Liu, Y. F., Ma, R. L., Wang, S. L., Duan, Z. Y., Zhang, J. H., Wu, L. J.
and Wu, C. F. Expression of an antitumor-analgesic peptide from the venom
of Chinese scorpion Buthus martensi Karsch in Escherichia coli. Protein
Expr Purif. 2003; 27 2, pp. 253-258.
Omran M A. Cytotoxic and apoptotic effects of scorpion Leiurus
quinquestriatus venom on 293T and C2C12 eukaryotic cell lines. J Venom
Anim Toxins incl Trop Dis 2003; 9(2):255-76. Rajendra, W., Arunmozhiarasi,
A., Jeyaseelan, K. Toxins in anti-nociception and anti-inflammation.
Toxicon; 2004 44 1, pp 1-17. Xiong, Y. M., Lan, Z. D., Wang, M., Liu, B.,
Liu, X. Q. Molecular characterization of a new insect neurotoxin with an
analgesic effect on mice from the scorpion Buthus martensi Karsch. Toxicon
1999; 37 8, pp. 1165-1180.
In summary, the present invention is a polarized dilute scorpion venom
solution, a method for making a polarized dilute scorpion venom solution,
and a method for administering dilute scorpion venom solution. The
polarized dilute scorpion venom solution relieves pain, improves
immune-system response, treats cancer, prevents cancer, improves quality
of sleep, reduces inflammation, and minimizes negative biological response
to chemotherapy and radiation treatment.
Claim 1 of 1 Claim
1. A method of magnetically polarizing
blue scorpion venom, comprising the steps of: diluting a blue scorpion
venom in a distilled water to create a dilute scorpion venom solution;
circulating said dilute scorpion venom solution through an one or more
plastic tubes; placing a series of flat magnets along said one or more
plastic tubes in pairs and on an one or more opposite sides of said one or
more plastic tubes, wherein said series of flat magnets are aligned so
that an one or more negative poles and an one or more positive poles of
said series of flat magnets mirror one another such that said series of
flat magnets repel one another; compressing said series of flat magnets
together with a clamp so that said series of flat magnets remain in place,
wherein said series of flat magnets that are compressed together also
compress said one or more plastic tubes such that said dilute scorpion
venom solution is forced to flow through said one or more plastic tubes in
close proximity to said series of flat magnets; recirculating said dilute
scorpion venom solution is polarized. ____________________________________________
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